Top 7 Tick Illnesses in the Midwest
September 03, 2026







A single tick bite can transmit bacteria, viruses or parasites, causing illnesses that range from mild to life-threatening. Here are the top tick-borne diseases and symptoms to watch for.
Lyme Disease
Found in: Deer Tick
Risk of Disease Transmission: Common
Symptoms:
- Bull’s-eye rash (not always present)
- Fever
- Fatigue
- Headache
- Muscle and joint aches
Health Risks of the Disease: Usually curable with antibiotics, but untreated infection can lead to arthritis, heart and nervous system problems.
Anaplasmosis
Found in: Deer Tick
Risk of Disease Transmission: Common
Symptoms:
- Fever
- Headache
- Chills
- Muscle aches
Health Risks of the Disease: Most people recover with prompt antibiotics, but severe illness can occur if treatment is delayed.
Alpha-Gal
Found in: Lone Star Tick
Risk of Disease Transmission: On the Rise
Symptoms:
- Delayed allergic reaction after eating red meat, including:
- Hives
- Stomach pain
- Anaphylaxis
Health Risks of the Disease: Can range from mild to life-threatening allergic reactions to red meat or dairy.
Babesiosis
Found in: Deer Tick
Risk of Disease Transmission: On the Rise
Symptoms:
- Fever
- Chills
- Fatigue
- Muscle aches
Some people have no symptoms.
Health Risks of the Disease: Can become severe or life-threatening in older adults, people without a spleen or those with weakened immune systems.
Ehrlichiosis
Found in: Lone Star Tick and Deer Tick
Risk of Disease Transmission: On the Rise
Symptoms:
- Fever
- Chills
- Headache
- Muscle aches
- Nausea
- Sometimes a rash
Health Risks of the Disease: Usually responds to antibiotics, but delayed treatment can lead to severe illness or death.
Rocky Mountain Spotted Fever
Found in: American Dog Tick, Brown Dog Tick, Lone Star Tick, Rocky Mountain Wood Tick
Risk of Disease Transmission: Rare
Symptoms:
- Sudden fever
- Severe headache
- Rash
- Nausea
- Muscle pain
Health Risks of the Disease: Can be fatal without early antibiotic treatment, making prompt diagnosis critical.
Powassan
Found in: Deer Tick
Risk of Disease Transmission: Rare
Symptoms:
- Fever
- Headache
- Vomiting
Severe cases can cause confusion, seizures and brain inflammation
Health Risks of the Disease: Rare but can cause permanent neurological damage or death.
Tags: Infectious Disease, Lyme Disease