Mehdi H. Shishehbor, DO, MPH, PhD

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Illustration of vascular vessel and bone scan depicting collaboration between Cardiovascular and Orthopaedics.

Cardiovascular and Orthopaedic Teams at University Hospitals Join to Lead First American Prospective Study of Bone Surgery Option for Chronic Limb-Threatening Ischemia

Innovations in Cardiovascular Medicine & Surgery | January 2026

LimFlow

LimFlow Technology Redefines Biology: Reverses Blood Flow to Prevent Limb Amputations

Mehdi Shishehbor, DO, MPH, PhD, explains how his team is developing preventative solutions to overcome chronic limb-threatening ischemia.

Example of intravascular imaging via (A) optical coherence tomography, published J Am Coll Cardiol Intv. Jan 17, 2024. Epublished DOI: 10.1016/j.jcin.2023.11.040

International Panel Provides Important Guidance on Treatment of Below-the-Knee Disease in Chronic Limb-Threatening Ischemia

Innovations in Cardiovascular Medicine & Surgery | February 2024

LimFlow procedure pre and post results

University Hospitals Team Treats Case of No-Option CLTI with “Off-the-Shelf” Percutaneous Deep Vein Arterialization

Patient faced the prospect of a second major amputation - Innovations in Cardiovascular Medicine & Surgery | Fall 2023

University Hospitals Cardiologists Reimagine Care Delivery in the Era of Coronavirus

Early learnings from COVID-19 - Innovations in Cardiovascular Medicine & Surgery | Summer 2020

Systemwide Limb Salvage Advisory Council Launched

Novel multidisciplinary activations are preventing amputation - Innovations in Cardiovascular Medicine & Surgery | Fall 2019

LimFlow Offers Hope for No Option CLI Patients

Minimally invasive technique provides endovascular venous arterialization Innovations in Cardiovascular Medicine & Surgery – Fall 2018 Mehdi H. Shishehbor, DO, PhD, MPH A breakthrough First in Man (FIM) clinical trial within the Harrington Heart &...

UH is First Hospital System in the Nation to Earn Coveted ACC Chest Pain Center Version 6 Accreditation

The highest quality in treating chest pain Innovations in Cardiovascular Medicine & Surgery – Fall 2018 Mehdi Shishehbor, DO, MPH, PhD In May 2018, a seven-months-long process involving reams of patient data, hundreds of documents and hours of...

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