Loading Results
We have updated our Online Services Terms of Use and Privacy Policy. See our Cookies Notice for information concerning our use of cookies and similar technologies. By using this website or clicking “I ACCEPT”, you consent to our Online Services Terms of Use.

Clinical Trial Highlights - Acute Leukemias and MDS

Share
Facebook
Twitter
Pinterest
LinkedIn
Email
Print

Hematology Update - Fall 2017

Acute Myeloid Leukemia – Newly Diagnosed

DCSK1916. Quizartinib With Standard of Care Chemotherapy and as Maintenance Therapy in Patients with Newly Diagnosed FLT3-ITD(+) AML
clinicaltrials.gov #NCT02668653
Local PI: Brenda Cooper, MD

GSI1916. Entospletinib Monotherapy and in Combination With Chemotherapy in Adults With Acute Myeloid Leukemia
clinicaltrials.gov #NCT02343939
Local PI: Benjamin Tomlinson, MD

HLSN1917. A Phase III, Double-Blind, Placebo-Controlled, Multicenter, Randomized Study of Pracinostat in Combination with Azacitidine in Patients ?18 Years with Newly Diagnosed Acute Myeloid Leukemia (AML) Unfit for Standard Induction Chemotherapy
clinicaltrials.gov # NCT03151408
Local PI: Brenda Cooper, MD

UCCC1915. Nivolumab in Eliminating Minima Residual Disease and Preventing Relapse in Patients with Acute Myeloid Leukemia in Remission after Chemotherapy (MAINTENANCE THERAPY TRIAL)
clinicaltrials.gov #NCT02275533
Local PI: Brenda Cooper, MD

Relapsed Acute Leukemias or MDS

DFCI1917. A Phase 1 Study of Ipilimumab in Combination with Decitabine in Relapsed or Refractory Myelodysplastic Syndrome/Acute Myeloid Leukemia
clinicaltrials.gov #NCT02890329
Local PI: Benjamin Tomlinson, MD

AGLA1916. A Multiple Dose, Dose Escalation Trial of AEB1102 in Patients with AML or MDS
clinicaltrials.gov #NCT02732184
Local PI: Benjamin Tomlinson, MD

ADCT1916. Study of ADCT-402 in Patients with Relapsed or Refractory B-cell Lineage Acute Lymphoblastic Leukemia (B-ALL)
clinicaltrials.gov #NCT02669264
Local PI: Benjamin Tomlinson, MD

Novel Allogeneic Stem Cell Transplant for Acute Leukemias

ACTN1916. Study of Iomab-B Prior to Hematopoietic Stem Cell Transplant Versus Conventional Care in Older Subjects With Active, Relapsed or Refractory AML.
clinicaltrials.gov #NCT02129582
Local PI: Benjamin Tomlinson, MD

CASE9Z13. Targeted Marrow Irradiation, Fludarabine Phosphate, and Busulfan Before Donor Progenitor Cell Transplant in Treating Patients with Hematologic Malignancies
clinicaltrials.gov #NCT02129582
Local PI: Paolo Caimi, MD

CASE1916. Inotuzumab Ozogamicin Post-Transplant for Acute Lymphocytic Leukemia
clinicaltrials.gov #NCT03104491
Local PI: Leland Metheny, MD

Share
Facebook
Twitter
Pinterest
LinkedIn
Email
Print