Left Atrial Appendage Closure
A female patient having consultation with doctor

Left Atrial Appendage Closure: An Alternative to Blood Thinners for Some Patients with AFib

The left atrial appendage (LAA) is a small, pouch-like sac in the top left chamber of the heart. It is where more than 90 percent of stroke-causing clots are formed. Closing the pouch prevents blood clots that may form there from entering the blood stream, traveling to the brain and causing stroke. LAA closure permanently closes the pouch and offers a lifetime alternative to blood thinning medications to prevent stroke in patients with AFib.


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Left Atrial Appendage Closure at University Hospitals: Facts at a Glance

  • 1800+ successful procedures performed
  • 99% first-attempt success rate
  • Same-day discharge for 95% of patients
  • All FDA-approved devices available (WATCHMAN™ FLX, Amplatzer Amulet)
  • Covered by Medicare and most insurance plans

Are You a Candidate for Left Atrial Appendage Closure (LAAC)?

You may qualify for LAAC, also known as the WATCHMAN procedure, if you have AFib and meet one or more of these criteria:

  • You cannot tolerate blood thinners. You experience side effects, allergic reactions or other contraindications to anticoagulants.
  • You have a history of bleeding complications. You have experienced prior gastrointestinal bleeding, intracranial hemorrhage or other major bleeding events.
  • You are at a high risk for falls. You have balance issues or mobility concerns that increase your risk for falling and injury while taking blood thinners.
  • Your occupation or lifestyle is not compatible with blood thinners. Your activities put you at risk for injury, you travel frequently and have limited access to necessary lab testing, or you simply cannot adhere to prescribed blood thinner medications.

What Should LAAC/Watchman Patients Expect Before, During and After the Procedure?

Left atrial appendage closure is a minimally invasive procedure in which a small, umbrella-shaped device is inserted through a thin tube, or catheter, threaded from your groin to your heart. The device seals off the left atrial appendage – the small pouch where blood clots typically form in AFib patients — reducing stroke risk without the need for long-term blood thinners. The procedure takes about 30 minutes and is performed under conscious sedation or “twilight” anesthesia.

Before the Procedure

The University Hospitals team will verify your insurance coverage and handle pre-authorization to minimize delays. You’ll undergo a CT scan to visualize your heart anatomy. Your blood thinner medications may be adjusted according to a personalized timeline provided by your care team.

Day of the Procedure

You’ll arrive 1-2 hours before your scheduled procedure for final checks and IV placement. Once in the procedure room, you’ll receive anesthesia to keep you asleep and comfortable. Our team will monitor your vital signs throughout the procedure. After the device is successfully positioned and released, you’ll recover in a monitored area for three hours before discharge. You’ll receive written discharge instructions, activity restrictions and a follow-up appointment with your primary provider (typically at 14 days). You can resume light activities immediately upon discharge.

After the Procedure

Three months after the procedure, you’ll have a repeat CT scan to confirm the device is positioned and functioning properly. Your blood thinner regimen may be discontinued or modified based on your specific condition and risk factors. Most patients resume normal activities, including strenuous exercise, one week after the procedure.

What Are Your Treatment Options With AFib?

If you cannot tolerate blood thinners, have a history of bleeding or prefer a permanent solution to stroke prevention, LAAC is a one-time procedure that offers lifetime protection against stroke without the need for blood thinners.

Managing AFib Stroke Risk: Treatment Options
Blood Thinners LAAC/WATCHMAN No Treatment
What it is Daily medication for life One-time procedure No intervention
Effectiveness Reduces stroke risk by ~70% 99% first-attempt success rate 5x higher (or more) stroke risk
Monitoring Monthly lab tests & medication refills One-time imaging study at 3 months (typically CT scan) then none required Regular doctor visits only
Bleeding risk 2-3% annual major bleeding risk Minimal after healing N/A

An Experienced Team

Patient Story: “LAAC gave me freedom from blood thinners.”

Stacy Joslin of Conneaut, Ohio was diagnosed with AFib at age 57 and prescribed blood thinners for life. Concerned about long-term medication side effects like nausea, dizziness and bruising, she explored alternatives. After meeting with Dr. Steven Filby, Joslin chose the WATCHMAN device. “The experience was very good. I was released home that same day,” she said. “I'm off my blood thinner medication, and I now feel better than I did before I started taking it. I don't have to deal with bothersome side effects.”

University Hospitals Harrington Heart & Vascular Institute is one of the busiest LAAC centers in the country – the sixth-busiest among 155 U.S. centers performing this procedure. That kind of volume means our team is equipped to handle every case with confidence and expertise. With a greater-than 99% success rate and groundbreaking research, we’ve earned national recognition as a Center of Excellence for LAAC.

Our doctors are actively advancing how LAAC is performed. We lead research studies and host training courses that attract heart specialists from across the country who want to learn from our team. With our commitment to staying on the cutting edge of the WATCHMAN procedure, you benefit from the latest techniques and knowledge.

We offer every FDA-approved LAAC device available, so your doctor can choose the one that best fits your heart’s anatomy. And when your procedure is done, most patients go home the same day. Our Cardiac Device Clinic handles all your follow-up care, so you get seamless monitoring and support long after implant.

When you choose UH for LAAC, you’re choosing a nationally recognized leader with the experience, outcomes and dedication to give you the best possible care.


Concomitant Catheter Ablation With LAAC

In addition to being performed as a solo operation, LAAC is sometimes done as part of a combined procedure with catheter ablation. Catheter ablation is a minimally invasive procedure that uses targeted energy to correct the abnormal heart rhythms of AFib. By destroying small areas of tissue in the heart responsible for irregular electrical signals, catheter ablation can restore a normal heart rhythm for many patients, reducing symptoms and the need for lifelong medication.

When LAAC and catheter ablation are done in a combined procedure, it’s called concomitant catheter ablation with LAAC. The combined procedure offers AFib symptom relief and reduced risk of stroke long term. Recovery from concomitant catheter ablation with LAAC is typically similar to recovery from either LAAC or catheter ablation performed alone.

Watch the AFib and Stroke Risk Webinar

Watch the Stroke Prevention in Patients with AFib Video

Learn More About Alternatives to Blood Thinners for AFib

Frequently Asked Questions About the LAAC/Watchman Procedure


Are You Considering LAAC Treatment?

If you have AFib and cannot safely take blood thinners due to bleeding history, frequent falls or medication intolerance, ask your primary care doctor or cardiologist for a referral to UH’s structural heart specialists.

Our expert team will determine whether you are a candidate for the LAAC procedure using a simple process: We’ll review your AFib history, lifestyle and bleeding events, and calculate your stroke and bleeding risk. If LAAC is appropriate, your care team will develop a care plan that includes LAAC implantation as part of long-term stroke prevention. After a few months on dose-reduced blood thinners following LAAC implant, most patients transition to aspirin alone for life.


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Reviewed by Steven Filby, MD, March 2026
Interventional Cardiologist, University Hospitals Harrington Heart & Vascular Institute