Wesley Center for Immunotherapy

The Wesley Center for Immunotherapy at UH Seidman Cancer Center

The Wesley Center for Immunotherapy is named in honor of Kimberly and Joseph Wesley, whose $10 million gift supports groundbreaking research to advance life-extending immunotherapies for patients. The Center is a state-of-the-art cellular therapy facility at the forefront of cancer care, where physician-scientists develop CAR T-cell, NK cell, and other cell-based therapies onsite.

The Wesley Center for Immunotherapy is one of only a few nationwide to successfully manufacture CAR T-cell therapy for human use, using a patient’s own immune cells to fight cancer.

At the Wesley Center for Immunotherapy, UH experts are creating cells for CAR T-cell treatment in a rapid one-day manufacturing protocol that can be administered a few days later. This is an improvement over the previous eight-day manufacturing process and vastly different from getting CAR T-cells from a commercial vendor, which can take three to four weeks for a patient’s specifically modified cells to even arrive. This innovation allows UH Seidman Cancer Center physicians to deliver therapy in a timely manner and to more patients than would otherwise be possible. In fact, researchers at UH are developing a CAR-T cell therapy line that will require only standard phlebotomy T-cell collection to produce CAR-T cells, making it possible in the near future to offer CAR T-cell therapy in other locations.

Showing    of 25 results

CAR T cell therapy in Multiple myeloma (MM) - isometric view 3d illustration.

“Compound A” Could Make Multiple Myeloma More Visible to Naturally Occurring T Cells, UH Seidman Research Suggests

Innovations in Cancer

Tyler Miller, MD standing in front of computer screen with another person sitting in chair looking at image of CAR T scan.

UH Seidman Researcher Parlaying Findings in Nature into More Effective Immunotherapy for Brain Tumors, Targeting Myeloid Cells

Innovations in Cancer

Koen van Besien, MD, PhD

UH Seidman Expert Argues for More Focus on Combination Haplo-Cord Transplant

Innovations in Cancer | January 2025

CAR T cell therapy in UH Wesley Center laboratory

Multiple Myeloma Patients at UH Seidman Cancer Center Have New Immunotherapy Option

BAFF CAR T has important advantage for these patients - Innovations in Cancer | July 2024

Neck cancer illustration

University Hospitals Seidman Cancer Center Launches Biotech Collaboration to Discover Cellular Immunotherapies for Head and Neck Cancer

Innovations in Ear, Nose & Throat | Winter 2023

Getty image lung cancer cell division

UH Seidman Cancer Center at ASH 2022

Innovations in Cancer | Winter 2023

UH Wesley Center Lab

Expansion of Wesley Center for Immunotherapy at University Hospitals Seidman Cancer Center Officially Opens

Addition brings more life-extending treatments and groundbreaking research to Northeast Ohio

CAR T illustration

UH Seidman Researchers Slash Time Needed to Produce CAR T-Cells

Quicker process will get needed therapy to cancer patients who don’t have time to wait - Innovations in Cancer | Fall 2022