Brain Tumor & Glioblastoma Clinical Trials in Northeast Ohio

With groundbreaking clinical trials, UH Seidman Cancer Center’s physicians have established many innovations in treating glioblastoma and other brain cancers in collaboration with the UH Neurological Institute’s Brain Tumor and Neuro-Oncology Center. Our patients have access to the most current clinical trials, treatments, and procedures unavailable at other facilities.

Interested in Participating in a Brain Tumor Study or Trial?

Learn more about participating in our research studies and clinical trials by browsing our actively recruiting studies & trials below.

You may also sign up online or call 1-800-641-2422 today.

Actively Recruiting Studies & Trials

PVSRIPO and Pembrolizumab for Recurrent Glioblastoma

Determine the Tolerance, Safety and Efficacy of PVSRIPO and Pembrolizumab in Patients with Recurrent Glioblastoma.

Glioblastoma (GBM) AGILE Trial

A Major Step Toward Precision Medicine for Malignant Brain Tumors

Recurrent GBM (RGBM) & LITT Trial

Laser Interstitial Thermotherapy (LITT) Combined With Checkpoint Inhibitor for Recurrent GBM (RGBM).


Ranked as one of the best cancer hospitals in the country by U.S. News & World Report for over 20 consecutive years, UH Seidman Cancer Center is a member of the Adult Brain Tumor Consortium, one of 11 elite Brain Tumor Centers of Excellence, and is part of the National Cancer Institute (NCI)-designated Case Comprehensive Cancer Center at Case Western Reserve University School of Medicine – one of an elite group of 51 comprehensive cancer hospitals nationwide. The Case Comprehensive Cancer Center has an “Exceptional” rating from the NCI, a rating only seven NCI-designated comprehensive cancer centers currently hold.

U.S. News & World Report ranking awarded to UH Cleveland Medical Center, University Hospitals’ flagship academic medical center.

Patient Stories

UH Neuro-Oncology patients tell their story.