Northeast Ohio’s Most Comprehensive Program for Sickle Cell Disease in Children

The Sickle Cell Anemia Center offered at the Angie Fowler Adolescent & Young Adult Cancer Institute at University Hospitals Rainbow Babies & Children’s Hospital is home to the largest inherited blood disorders program in northeast Ohio. In cooperation with local and regional pediatricians and family physicians, we help more than 250 children manage the disease and reach their full potential as thriving adults.

Sickle cell disease is discovered within the first 24 hours your newborn enters this world. A blood test checks for the defective form of hemoglobin, a protein in red blood cells, that causes sickle cell disease. This sickle cell test is a required newborn screening at every hospital nationwide.

Our specialists are available to provide treatment and long-term health management for children and young adults with all types of sickle cell disease. Since 1989, we have participated in national research projects to ensure our patients are on the leading edge of sickle cell care.

Multidisciplinary Team of Pediatric Experts for Patients Living with Sickle Cell Disease

Our fellowship-trained, board-certified specialists understand the challenges for children with sickle cell anemia. Sickle cell disease is an inherited condition in which the body does not produce enough healthy red blood cells to carry oxygen throughout the body. This can cause severe pain. It can also harm organs, muscles and bones. Our sickle cell management team proactively monitors any potential complication or complexity that may impact your child.

By working collaboratively, we do everything we can to prevent these complications, and help patients manage the ones that arise. Our patients also enjoy the convenience of being able to see the specialists they need, all in one place. Our highly skilled doctors are experts in the following areas:

  • Blood diseases (hemoglobinopathy)
  • Brain and nervous system (neurology)
  • Eye diseases (ophthalmology)
  • Genetics counseling
  • Heart diseases (cardiology)
  • Lung diseases (pulmonology)
  • Nutrition
  • Reproductive health (gynecology)
  • School intervention

Personalized and Innovative Sickle Cell Disease Treatments

There are a number of innovative therapies and treatments available for sickle cell patients today. We have an active research program so our care team can stay ahead of the latest medical advances. Our primary goal is to keep your child as healthy and comfortable as possible.

Once diagnosed, our multi-disciplinary team of experts collaborates to care for your child from infancy through young adulthood. We also work together to guide the transition into adult care. We are committed to providing the lifelong care you and your child need with compassion, expertise and a community of support.

Our preventative-centered approach to care helps minimize symptoms and avoid complications. Therapies and treatment options for children with sickle cell disease include:

We work with each patient and family to determine the best course of treatment for their particular situation.

UH Sickle Cell Anemia Center Welcomes New Patients and Referrals

The Sickle Cell Anemia Center at University Hospitals Rainbow Babies & Children’s Hospital’s Angie Fowler Adolescent & Young Adult Cancer Institute in Cleveland, Ohio invites patients and their families to contact us and make an appointment with our knowledgeable team. In addition, physicians can refer a patient to the Sickle Cell Anemia Center at UH.

For appointments at UH Rainbow Babies & Children’s Hospital, call 877-390-4293. Referrals or questions can also be emailed to

Conveniently Located at UH Cleveland Medical Center

The Sickle Cell Anemia Center is located on the 6th floor of the Bolwell Health Center at UH Cleveland Medical Center.

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