Blood Clot Study

Chronic Venous Thrombosis: Relief with Adjunctive Catheter-Directed Therapy (C-TRACT)

Scanning electron micrograph of a blood clot in human blood
AGE: >18 years old
TYPE: Observational and sample collection
CONDITION: Deep Vein Thrombosis (DVT), Post Thrombotic Syndrome (PTS)

Learn More About This Research Study

For more information, please contact Janelle Bennett, the study coordinator at 216-844-2399 or complete the online form below.

Study Purpose

The purpose of this study is to examine what the best treatment is for damage caused deep vein thrombosis (DVT). This damage can lead to a condition called Post Thrombotic Syndrome (PTS). In this study, patients with moderate to severe PTS will be randomized to either endovascular therapy (EVT) or no-EVT treatment groups. All study patients will be monitored closely and undergo optimal medical/compression and wound care as part of their treatments. The EVT arm patients will additionally be treated with advanced image-guided procedures that are currently used in standard practice. The study aims to understand which treatment strategy is most effective in improving patients’ symptoms, healing wounds and improve quality of life.

Who Can Participate

Participants 18 years of age and older with daily leg swelling or aching of at least moderate severity or presence of a venous leg ulcer and a history of previous DVT may be eligible for this study.

Request More Information

To learn more about this study, please fill out the form below to request more information.


Study ID

  • STUDY20201499