Blood Clot Study
Chronic Venous Thrombosis: Relief with Adjunctive Catheter-Directed Therapy (C-TRACT)
TYPE: Observational and sample collection
The purpose of this study is to examine what the best treatment is for damage caused deep vein thrombosis (DVT). This damage can lead to a condition called Post Thrombotic Syndrome (PTS). In this study, patients with moderate to severe PTS will be randomized to either endovascular therapy (EVT) or no-EVT treatment groups. All study patients will be monitored closely and undergo optimal medical/compression and wound care as part of their treatments. The EVT arm patients will additionally be treated with advanced image-guided procedures that are currently used in standard practice. The study aims to understand which treatment strategy is most effective in improving patients’ symptoms, healing wounds and improve quality of life.
Who Can Participate
Participants 18 years of age and older with daily leg swelling or aching of at least moderate severity or presence of a venous leg ulcer and a history of previous DVT may be eligible for this study.