Early-Phase Clinical Trials Program

University Hospitals Seidman Cancer Center

Afshin Dowlati, MD, Director, Center for Cancer Drug Development 216-844-1228, Afshin.Dowlati@UHhospitals.org
Christopher Hoimes, MD, Medical Oncology 216-844-5946, Christopher.Hoimes@UHhospitals.org
Jennifer Eads, MD, Medical Oncology 216-844-6003, Jennifer.Eads@UHhospitals.org

Please call Erica Gentile, New Patient Intake Coordinator, at 216-286-2292.
For hospital transfers, please call 216-844-1111.

Conditions Treated

  • Any recurrent or refractory cancers
  • Any cancer where standard therapy can be improved


  • New targeted therapies
  • Immunotherapy
  • Cell therapies
  • Cancer vaccines
  • Proton beam therapy

Distinguishing Features

  • Part of NCI-designated Case Comprehensive Cancer Center
  • Dedicated team with specialized expertise in early-phase clinical trials
  • Genomic evaluation for optimal selection of studies
  • Specialized Adolescent and Young Adult (AYA) cancer program
  • Access to new drugs in NCI portfolio as members of NCI Experimental Therapeutic Clinical Trials Network
  • Extensive portfolio of Phase I and Phase II treatment studies