X-Ray / Mammography Research

University Hospitals Department of Radiology and Case Western Reserve University has a variety of state-of-the-art radiographic, fluoroscopic, and mammographic technology for translational and clinical research. The infrastructure includes a wealth of equipment, support staff, and researchers with clinical and technical expertise. Please see below for a brief overview of the equipment, personnel, and areas of ongoing research.

Our state-of-the-art radiographic and fluoroscopic suites include clinical systems equipped with the latest advances in dual-energy imaging, digital tomosynthesis, 3D rotational angiography, and advanced visualization and postprocessing applications for vascular and interventional oncology applications.

The department also has a well-established track record in developing and validating computer-aided detection (CAD) technologies. Current research is underway to validate the clinical deployment of the latest generation of artificial intelligence-enabled tools to assist with rapid detection and diagnosis in radiographic images.

The breast imaging capabilities include digital mammography with digital breast tomosynthesis on systems equipped with high-definition detectors, synthetic full-field digital mammography, and contrast-enhanced spectral mammography features. Dedicated breast ultrasound with shear wave elastography is incorporated into routine clinical practice, and ongoing research; breast MRI is available using both standard diagnostic approaches and the novel fast breast MRI screening technique. In addition, UH Cleveland Medical Center, as well as several community-based clinical sites in the Northeast Ohio region, offer multimodality breast biopsy, using x-ray guided stereotactic breast biopsy, ultrasound-guided biopsy, and MRI-guided biopsy capabilities.

Research teams are built on strong collaborations between clinicians and basic science researchers to create a translational pipeline, bringing the latest technologies into the clinic and offering innovators a clinical translation and validation platform.