Genetic Susceptibility to Contact Lens-Related Microbial Keratitis

Purpose of Study

To determine if there are genetic differences between contact lens wearers that get bacterial corneal infections and those that do not.

Basic Eligibility Criteria


  • Healthy contact lens wearers (using contacts for at least 5 years)
  • Ages 15-70 years
  • European ancestry
  • No history of a corneal ulcer from contact lenses


  • Contact lens wearers who have had an infection in the cornea (infection related to contact lens wear)
  • Ages 15-70 years at the time of infection
  • European ancestry
  • Must be willing to provide blood sample or saliva sample

How to Contact Us

Principal Investigator: Loretta Szczotka-Flynn, OD, PhD
Study Coordinator: Sangeetha Raghupathy | 216-844-8552

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