Clinical Trials

The Vision Research Coordinating Center (VRCC) is a joint collaboration between the UH Eye Institute and the CWRU Department of Ophthalmology and Visual Sciences. The center was established in 2004 to coordinate all ophthalmic clinical trials contracted through UH or CWRU. Descriptions of some of the current clinical trials are listed below, categorized by area:

Cornea & Contact Lens Studies

Genetic susceptibility to contact lens-related microbial keratitis

Post Corneal Transplant - Scleral Lens Wear Study

Zoster eye disease study (ZEDS)

Kowa Study

Genetic factors in keratoconus study

Soft Contact Lens Study

Retina Studies

DRCR Protocol AC

Aflibercept vs. Bevacizumab with deferred aflibercept for diabetic macular edema

Oxurion NV Study

A Phase 2, randomized, multicenter study to assess the dose level of multiple THR 149 injections and to evaluate the efficacy and safety of THR-149 versus aflibercept for the treatment of diabetic macular edema (DME)

IONIS-FB-LRX Study

Study to Assess Safety and Efficacy of Multiple Doses of IONIS-FB-LRX in Patients with Geographic Atrophy Secondary to Age-Related Macular Degeneration

Glaucoma Studies

Study Integrating Glaucoma and Eye Health Translation

Pediatric Ophthalmology Studies

Cerebrotendinous xanthomatosis (CTX) study in patient populations diagnosed with early onset idiopathic bilateral cataracts

Study to compare afibercept to laser therapy in babies who have Retinopathy of Prematurity (ROP)

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