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Radiation Oncology Research
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Robust Clinical Trial Portfolio

To prove a new treatment or biomarker is safe, effective, and adds value to patients' lives, they must undergo clinical trial testing. UH Seidman Cancer Center consistently accrues many participants in national cooperative group trials and has a nationally renowned phase I program. Furthermore, we have led many landmark meta-analyses of randomized trials to understand better which patients benefit from specific treatment approaches.

University Hospitals Cleveland Medical Center, in conjunction with Case Western Reserve University and UH Seidman Cancer Center, is a part of the UH Clinical Trials Unit, which provides a centralized infrastructure to support cancer-related research. The CTU's mission is to provide the highest quality nursing, data management, regulatory, financial, and quality assurance services for the conduct of clinical trials for the benefit of our patients and investigators. In addition, many of our University Hospitals Seidman Cancer Center clinical trials are offered at regional sites close to home for patients.

We have a robust cancer clinical trial portfolio at UH Seidman Cancer Center and Case Comprehensive Cancer Center, with over 500 active recruiting trials and over 100 clinical trials involving radiotherapy.

Total Cancer Trials

527

Radiotherapy Trials

109

Extensive Participation in Clinical Trials

Faculty members of the Radiation Oncology Department participate in clinical trials of various cooperative groups, including:

  • Alliance for Clinical Trials in Oncology (ACOSOG)
  • American College of Radiology Imaging Network (ACRIN)
  • Children’s Oncology Group (COG)
  • Gynecologic Oncology Group (GOG)
  • North Central Cancer Treatment Group (NCCTG)
  • National Surgical Adjuvant Breast and Bowel Project (NSABP)
  • Radiation Therapy Oncology Group (RTOG)
  • Eastern Cooperative Oncology Group (ECOG)

There are several funded projects in the department in which some of the physics faculties, along with the faculties from radiation oncology and radiation biology, are involved as principal investigators (PIs), Co-PIs, and Co-Investigators (Co-Is).