Diabetes and Other Endocrine and Metabolic Disorders

Achondroplasia is a group of rare genetic (inherited) bone disorders. Achondroplasia is the most common type of what was once called dwarfism, in which the child's arms and legs are short in proportion to body length.

When a child's gender is in question at birth, the child has atypical genitalia (ambiguous genitalia). This means that the genitals don't seem to be clearly male or female.

Detailed information on the endocrine system, its anatomy and function, including a full-color, labeled illustration

Detailed information on anterior pituitary disorders, including hypopituitarism

Detailed information on disorders affecting the adrenal glands, including underactive adrenal glands (Addison's disease), overactive adrenal glands (Cushing's syndrome), and pheochromocytoma

Detailed information on disorders affecting calcium metabolism, including juvenile osteoporosis, hyperparathyroidism, hypoparathyroidism, and DiGeorge syndrome

Detailed information on disorders affecting the pituitary gland, including posterior anterior disorders and anterior pituitary disorders

Detailed information on disorders affecting the thyroid gland, including hyperthyroidism (Graves disease) and hypothyroidism

Detailed information on diabetes, including type 1 diabetes, type 2 diabetes, teens and diabetes, and diet and diabetes

Puberty that happens late is called delayed puberty. This means a child's physical signs of sexual maturity don’t appear by age 12 in girls or age 14 in boys. This includes breast or testicle growth, pubic hair, and voice changes. These are known as secondary sexual characteristics.

Diabetes insipidus is a condition caused by not enough antidiuretic hormone (ADH) in the body. ADH is also known as vasopressin. This is a hormone that helps the kidneys keep the correct amount of water in the body. The condition is also called “water diabetes.”

Diabetes occurs when not enough insulin is made. Or when the body is unable to use the insulin that is made. The 3 main types of diabetes are type 1, type 2, and gestational diabetes.

It is important to learn about proper meal-planning when your child has diabetes. The type and amount of food your child eats affects his/her blood sugar levels.

Growth hormone (GH) deficiency is when the pituitary gland doesn't make enough growth hormone. GH is needed to stimulate growth of bone and other tissues. This condition can occur at any age. GH deficiency does not affect a child's intelligence.

Puberty that happens early is called precocious puberty. Gonadotropin-independent precocious puberty is caused by early secretion of high levels of sex hormones. These include the male androgens and female estrogens.

Graves disease is an autoimmune disease. The immune system normally protects the body from germs with chemicals called antibodies. But with an autoimmune disease, it makes antibodies that attack the body’s own tissues. With Graves disease, antibodies cause the thyroid gland to make too much thyroid hormone. This is known as hyperthyroidism. Extra thyroid hormone in the bloodstream leads to the body's metabolism being too active.

A growth problem means that a child falls either below or above the average range of growth for a child's age, sex, family history, or racial background.

Detailed information on growth in children, including normal growth, newborn screening tests, growth problems, growth hormone deficiency, and achondroplasia

Hyperparathyroidism is when the parathyroid glands make too much parathyroid hormone. The condition is rare in children.

Hypoparathyroidism is when the parathyroid glands don’t make enough parathyroid hormone. The parathyroid glands are 4 tiny glands on the thyroid. The hormone they make helps manage levels of calcium in the bloodstream. Low levels of the hormone leads to low levels of calcium. This can lead to muscle spasms and cramping, called tetany.

Hypoglycemia is when the level of sugar (glucose) in the blood is too low. Glucose is the main source of fuel for the brain and the body. The normal range of blood glucose is about 70 to 140 milligrams per deciliter (mg/dL). The amount blood differs based on the most recent meal. Babies and small children with type 1 diabetes will have different goal ranges of blood glucose levels.

Hypoglycemia is when the level of sugar (glucose) in the blood is too low. Glucose is the main source of fuel for the brain and the body. In a newborn baby, low blood sugar can happen for many reasons. It can cause problems such as shakiness, blue tint to the skin, and breathing and feeding problems.

Hypopituitarism means that the pituitary gland is not working normally. The pituitary gland is a pea-sized gland located at the base of the brain. It’s the master endocrine gland in the body. The pituitary gland normally releases as many as 8 different hormones. These hormones control growth, metabolism, blood pressure, and other body processes. The effects of hypopituitarism may be slow over time. Or they may be sudden.

Hypothyroidism is when the thyroid gland does not make enough thyroid hormone. Congenital hypothyroidism is when the disorder is present in a baby at birth. If not treated, it can lead to serious health problems.

Detailed information on diabetes and other endocrine and metabolic disorders that affect children

Osteoporosis is a condition where the bones are thinner than normal. It’s a condition that gets worse over time. This means that bones get thinner over time, or don’t grow as they should. The bones are then weaker and at higher risk of breaking. The condition is much more common in older adults. But it can also occur during childhood. In children, it’s called juvenile osteoporosis.

A national program exists to screen all newborns for certain disorders within the first few days of life.

Cushing syndrome is a hormone disorder. It’s caused by having high levels of the hormone cortisol over a long time. Cushing syndrome is fairly rare. It most often affects adults who are 20 to 50 years old. But it can also occur in children. It is sometimes called hypercortisolism.

Detailed information on problems in puberty, including precocious puberty, gonadotropin-independent precocious puberty, and delayed puberty

Pheochromocytoma is a tumor of the adrenal glands. The tumor makes hormones called epinephrine and norepinephrine. This leads to an excess of the hormones in the body. These hormones help manage heart rate and blood pressure, and they have other tasks. Too much of these hormones in the body causes problems.

Detailed information on posterior pituitary disorders

Puberty that happens early is called precocious puberty. This means a child's physical signs of sexual maturity develop too soon. This includes breast growth, pubic hair, and voice changes. These are known as secondary sexual characteristics. Precocious puberty happens before age 8 in girls, and before age 9 in boys.

SIADH is when the body makes too much antidiuretic hormone (ADH). This is a hormone that normally helps the kidneys conserve the correct amount of water in the body. SIADH causes the body to retain water. This lowers the level of sodium in the blood. SIADH is rare. It most often happens to children who are in the hospital.

Detailed information on diabetes and other endocrine and metabolic disorders that affect children

Detailed information on special considerations for teenagers with diabetes

Diabetes is a condition in which the body can't make enough insulin, or can't use insulin normally. Type 1 diabetes is an autoimmune disorder. The body's immune system damages the cells in the pancreas that make insulin. Insulin is a hormone. It helps sugar (glucose) in the blood get into cells of the body to be used as fuel. When glucose can’t enter the cells, it builds up in the blood. This is called high blood sugar (hyperglycemia).

Diabetes is a condition in which the body can't make enough insulin, or can't use insulin normally. Type 2 diabetes is a metabolic disorder. Insulin is a hormone. It helps sugar (glucose) in the blood get into cells of the body to be used as fuel. When glucose can’t enter the cells, it builds up in the blood. This is called high blood sugar (hyperglycemia). High blood sugar can cause problems all over the body.

Addison disease is when the adrenal glands don't make enough of two steroid hormones. The hormones are cortisol and aldosterone. Cortisol controls the body's metabolism, blocks inflammatory reactions, and affects the immune system. Aldosterone manages sodium and potassium levels. Addison disease is fairly rare and may first appear at any age.

A look at average height and weight ranges for kids, based on age.

22q11.2 deletion syndrome is a genetic disorder that can cause many health problems. These problems may range from heart defects and developmental delays to seizures.

Back to Top