Stroke Research

Translating Clinical Research into Improved Stroke Patient Care

Clinical research at University Hospitals Neurological Institute’s Comprehensive Stroke Center in Cleveland, Ohio, is aimed at quickly translating basic science directly into improved patient care. Care at the Comprehensive Stroke Center is always shaped by the most innovative medical and surgical therapies because our experts continuously engage in research. Our affiliation with Case Western Reserve University School of Medicine allows basic science research to be quickly translated to findings that will improve patient care. Over the past several years, the Comprehensive Stroke Center has secured over $2 million in clinical research funding, the majority of it coming from the National Institutes of Health (NIH).

Understanding Clinical Trials

Clinical trials are research studies that involve the participation of human volunteers. The purpose of a clinical trial is to test the safety and effectiveness of new ways to diagnose, prevent and treat a medical problem, such as disease, illness or injury.

Being part of a clinical trial can be a chance for patients to receive new or additional treatment. While research may not always have a direct benefit to the participant, clinical trials can help scientists and doctors to learn and understand the better ways to help treat their patients and patients in the future.

Current Clinical Trials


StrokeNet is a new way of operating and conducting collaborative clinical National Institutes of Health (NIH) trials across the country. Cleveland has been chosen as a Regional Coordinating Center, which is comprised of the major health care institutions in the regions to conduct NIH stroke and neurology research. What makes this unique is that all institutions and the corresponding satellite hospitals will operate and conduct clinical research trials under one financial budget and contract and utilize one central Institutional Review Board (IRB). This will allow for us to maximize efficiencies in the development, promotion and conduct of multisite exploratory phase I, II and confirmatory phase III clinical trials in stroke prevention, treatment and recovery that are funded by NIH.

Some stroke trials that we conduct at University Hospitals enroll patients who are in the acute stage of their disease or injury. This means that patients are enrolled while they are in the emergency room, intensive care unit, or operating room. You can read about some of these trials below and at

For any questions about our current stroke studies, please contact Mary Andrews or Eileen Terrell:

Mary Andrews
Phone: 216-844-2386

Eileen Terrell
Phone: 216-844-2328