Covid-19 Research at UH
University Hospitals has a proud history of leading the way through innovation and research. As we face the unknown with COVID-19, it is inspiring that UH and the biomedical industry is coming together and assembling a variety of novel and innovative ideas to seek solutions to prevent, treat, and cure COVID-19.
Interested in Participating in a COVID-19 Study or Trial?
Learn more about participating in COVID-19 research studies and clinical trials by browsing our actively recruiting studies & trials below.
You may also sign up online or call 1-833-788-7425 today.
Actively Recruiting Studies & Trials
UH COVID-19 Biorepository
PI: Grace McComsey, MD
COVID-19 Longhauler Study
PI: Grace McComsey, MD
COVID-19 Children's Study
PI: Grace McComsey, MD
Effect of Covid-19 on Parkinson’s Disease, Dementia with Lewy Bodies, and Alzheimer’s
PI: Steven Gunzler, MD
COVID-19 Impact on Pregnancy & Postpartum Health
PI: Erika Kelley, PhD
Adolescent Depression Measured by qeeG Technology
PI: Molly McVoy, MD
Evaluation of Cardiopulmonary Reserve in Recovering COVID-19 Patients
PI: Sadeer Al-Kindi, MD
Lung Immunity to COVID-19
PI: Richard Silver, MD
Studies & Trials Not Actively Recruiting
- Protective Behaviors, Care Experience, and Health Outcomes of Underserved Cancer Patients During the COVID-19 Pandemic
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Principal Investigator: Cynthia Owusu, MD
This study is aims to understand how cancer patients protect themselves at home against COVID-19, what helps or hinders their prevention efforts, experiences of cancer and health care disruption, socioeconomic unmet needs, and the impact of these factors on their health during the pandemic. - Factors Influencing Nurses' Stress and Growth during the COVID-19 Pandemic
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Patricia Beam, DNP, RN, NPD-BC
This study aims to describe COVID-19 work-related disruption and personal exposure to nurses, the nature and frequency of organizational supports used by nurses and examine nurses’ positive and negative responses. - Blood Coagulation Findings in Hospitalized Pediatrics Patients with COVID-19
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Sanjay Ahuja, MD
The purpose of this study is to determine whether coagulation activation markers can predict the severity of illness in PIMS patients. The aims of the study are to describe the coagulation dysfunction in patients with PIMS, including abnormal coagulation screens, D-dimers, fibrinogen, and other markers of hemostasis by collecting data from the clinical records of patients to describe the coagulation abnormalities, and to correlate the abnormalities in the coagulation parameters to severity of illness and inflammatory markers such as CRP and ESR. - Prenatal Care Adequacy During COVID-19
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Kerri Brackney, MD
Dr. Brackney is conducting a retrospective cohort study comparing the change in adequacy of prenatal care for African American/Black and non-African American/Non-Black women before and during the COVID-19 pandemic, which will include a survey of postpartum women. The hypothesis of this study is that the COVID-19 pandemic caused changes in access to prenatal care that disproportionately and negatively affected African American/Black women. - Surveillance and Epidemiology of Perinatal COVID-19 Infection
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Anna Maria Hibbs, MD
The purpose of this study is to provide real-time cumulative information of mothers identified with active COVID-19 Infection. The study will collect the number of cases of COVID-19 infection among mothers who deliver at participating hospital, the likelihood of perinatal transmission of COVID-19 from mother to baby, the likelihood of post-natal transmission of COVID-19 from mother to baby and the risk factors associated with that transmission, the spectrum of disease severity in newborns with COVID-19 infection and the risk factors for more severe disease, the outcomes of infants with acquired COVID-19 infection, and the infection control procedures that hospitals are practicing (immediate maternal-newborn separation vs. rooming-in; direct nursing vs. expressed breast milk feedings; etc.). - Conception Planning in OBGYN
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Rachel Weinerman, MD
The purpose of this study is to collect self-reported data on conception planning in OBGYN, Reproductive Endocrinology, and Fertility Center patients during the COVID-19 pandemic. - SARS-CoV-2 Antibody Presence on Fertility Stimulation
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Rachel Weinerman, MD
Dr. Weinerman's study aims to study the effects of COVID-19 antibody presence on fertility stimulation and early pregnancy outcomes. - Understanding Coronavirus Disease 2019 in US Children
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Steven Shein, MD
The purpose of this study is to the SARS-CoV-2 infection among children, adolescents, and young adults hospitalized in the U.S., including how the immune systems of children and young adults work to prevent COVID-19 and to help them recover from it. - More Noteworthy COVID-19 Studies
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Clinical Trial with Novel Anti-Cancer Agent Used for Patients with COVID-19+ Cancer Patients
Afshin Dowlati, MDEpidemiology, Transmission and Immunology of COVID-19 in Nursing Home Residents
David Canaday, MDUnderstanding Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with COVID-19
Sahera Dirajlal-Fargo, DOEvaluation of modified chest X-ray techniques in COVID-19 Patients.
Robert Gilkeson, MDMachine Learning Analysis of COVID-19 Imaging
Amit Gupta, MDThe postmortem pathology of COVID-19: a multi-institutional autopsy case study
Holly Harper, MDCardiac Manifestations of COVID-19
Danilo Aurelio, MDDevelopment of Multi-Organ Magnetic Resonance Imaging (MRI) Technology for Covid-19 Patients
Chaitra Badve, MDCOVID-19 in Patients with Chronic Liver Diseases
Kenneth Chavin, MDImpact of Outpatient Glycemic Control on Outcome of COVID-19 in Patients with Diabetes.
Nadine El Asmar, MDShort and long term outcomes of patients hospitalized with COVID 19 pneumonia.
Jihane Faress, MDAssociation of imaging, clinical and laboratory findings in COVID-19 patients, with outcome characteristics
Robert Gilkeson, MDTelemedicine in Laryngology
N Scott Howard, MD, MBAOral host defense factors in COVID-19 infection
Jeffrey Jacobson, MDImmune Function And Resiliency Before And After Covid-19 Vaccination In Persons Living With Hiv Infection And Controls
Jeffrey Jacobson, MDPilot study to investigate the immunogenicity and safety of COVID-19 mRNA vaccines in select patient populations with immune based disorders
Jeffrey Jacobson, MDRisk of Thromboembolic Events in COVID-19 Patients
Stefanie Lehmier, MDWhole Genome Sequencing Analysis of SARS-CoV-2 Positive Patients
Grace McComsey, MDInvestigation of Gut and Mucosal Integrity in Covid Progression
Grace McComsey, MDRelationship between vitamins K and D and COVID-19 outcomes, acutely and after recovery
Grace McComsey, MDEvaluation of the physiological and immunological responses to COVID-19 vaccinations
Grace McComsey, MDLong term immunological responses of COVID-19 vaccination in cancer patients on chemotherapy
Alberto Montero, MDInnate And Adaptive Immune Cell Perturbations In Covid-19
Lalitha Nayak, MDHypercoagulability in COVID-19 Infections – Developing a Point-of-Care Device to Assess Prognosis
Lalitha Nayak, MDCoronavirus 2019 and Obstetric Transmission
Rachel Pope, MD, MPHCOVID and Intimate-Partner Violence
Rachel Pope, MD, MPHCOVID-19 and Bell's Palsy using the TriNetX platform
Cyrus Rabbani, MDMulticenter Study of COVID-19 Disease in Critically Ill Patients in the US: Examination of the Incidence, Risk Factors, Clinical Features, and Outcomes of Acute and Chronic Kidney Disease
Arash Rashidi, MDSite for The Severe Asthma Research Program (SARP) SARP IV Characterization and Longitudinal Follow-Up Protocol
Kristie Ross, MDDescription of COVID-19 epidemiology, diagnosis and management in nursing home patients.
Elie Saade, MDProof of Concept Safety Trial for S-Nitrosylation Therapy to Improve Oxygenation Status in Severe Covid-19 Patients Receiving Supplemental Oxygen Support
Robert Schilz, DOClinical outcomes in patients with cancer diagnosed with COVID19
Sadd Sheikh, MDMyocardial Infarction Presentation and Management in the Era of COVID-19
Mehdi Shishehbor, DO, MPH, PhDImpact of glycemic control on morbidity outcomes in diabetic patients with COVID-19 in the community hospital setting.
Catherine Wilson, MDRole of SARS-CoV-2-associated plasma exosomes in modulation of cytokine production
Min Yao, MD, PhDUsing Geospatial Mapping to Determine Risk Factors for Opioid Overdose among patients seen in an Urban Level-1 Trauma Center in Cleveland Ohio
Justin Yax, DOPre-exposure Immunologic Health and Linkages to SARS-COV2 Serologic Responses, Endothelial Cell Resilience, and Cardiovascular Complications: Defining the mechanistic basis of high risk endotypes. (Cardio-COVID)
David Zidar, MD, PhDVitamin D as an Immunomodulator to Prevent Complications and Reduce Resource Utilization in Outpatients (Telehealth Enabled Trial)
Kevin Cooper, MD
In the News: UH and COVID-19 View all Articles & News
Harrington Discovery Institute Advances COVID-19 Treatments
SARS-C0V-2 Task Force Accelerates Study of Impact of COVID-19
UH and CWRU Announce Study of AstraZeneca’s COVID-19 Vaccine Candidate
NASA, University Hospitals Join Forces in Response to COVID-19
Athersys and UH announce activation of first clinical site for MACOVIA study
Diaphragm Pacing System Used to Help COVID+ Patients
Harrington Discovery Institute: Transatlantic Call for Proposals for New COVID Treatments
UH Among First in Nation to Test Investigational Antiviral Drug Against COVID-19
Stronger Together
University Hospitals and Cleveland Clinic – COVID-19 Observations, Lessons Learned, Partnership and Roadmap for the Future.
Learn More
UH COVID-19 Research Publications
Characterizing COVID-19 Presentation and Clinical Outcomes in HIV Patients in the U.S.
George A. Yendewa, MD, Jaime Abraham Perez, PhD, Kayla Schlick, MS, Heather Tribout, BS, Grace McComsey, MD
Pediatric Patients with SARS-CoV-2 Infection: Clinical Characteristics in the United States from a Large Global Health Research Network
Ankita Desai, MD, Alexandra Mills, MBA, Sarah Delozier, PhD, Claudia Cabrera Aviles, MD, Amy Edwards, MD, Sahera Dirajlal-Fargo, DO, and Grace McComsey, MD
Clinical Characteristics, Hospitalization and Mortality Rates of COVID-19 among Liver Transplant Patients in the United States: A Multi-Center Research Network Study
Emad Mansoor, MD, Abe Perez, PhD, Mohannad Abou-Saleh, MD, Seth Sclair, MD, Stanley Cohen, MD, Gregory Cooper, MD, Alexandra Mills, MBA, Kayla Schlick, MS, and Ahmad Kahn, MD
Incidence of Bell Palsy in Patients With COVID-19
Akina Tamaki, MD, Claudia I. Cabrera, MD, Shawn Li, MD, Cyrus Rabbani, MD, Jason E. Thuener, MD, Rod P. Rezaee, MD, Nicole Fowler, MD