Sanford Markowitz, MD, PhD
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Specialty: Hematology and Oncology
View Expertise - Languages Spoken: English
Biography: Sanford Markowitz, MD, PhD
Expertise
Titles
- Professor, CWRU School of Medicine
Certifications & Memberships
- Medical Oncology - American Board of Internal Medicine
- Internal Medicine - American Board of Internal Medicine
Education
Fellowship | Medical Oncology
Medical Oncology - National Cancer Institute (Nci) (1984 - 1987)
Residency | Internal Medicine
Internal Medicine - University Of Chicago Medical Center (1982 - 1984)
Internship | Internal Medicine
Internal Medicine - University Of Chicago Medical Center (1981 - 1982)
Professional Education
Yale University (1981)
Medical Education
Yale University School Of Medicine (1980)
Undergraduate
Harvard University (1974)
Other Education
Harvard University (1974)
Awards
- Alumnus Investigator of the Howard Hughes Medical Institute
- Elected to American Society Clinical Investigation
- Elected to the Association of American Physicians
- Visiting Professorships at: Dana Farber Cancer Center, Harvard Medical School; Beth Israel Deaconess Medical Center, Harvard Medical School; Cornell-Weill Medical College
- Recipient, Sadie Gerson Distinguished Scholar Award for Contributions to Colon Cancer (University of Pittsburgh)
- Recipient Ohio State University Cancer Genetics Program Commemorative Medal
- Harrington Discovery Institute Scholar Innovator Award
- Case Western Reserve University Distinguished Research Award
- Case Western Reserve University Distinguished University Professor
About
Sanford Markowitz, MD, PhD, holds the Markowitz-Ingalls Professorship of Cancer Genetics at the Case Western Reserve University School of Medicine, with appointments in the Department of Medicine and in the Case Comprehensive Cancer Center, and co-appointments in the Departments of Genetics and Genome Sciences and in Molecular Biology and Microbiology. He is internationally recognized for his work identifying key genetic causes of colon cancer and developing molecular tests for early cancer detection. In clinical practice he is an attending physician at the UH Seidman Cancer Center.
Dr. Markowitz’s laboratory studies molecular abnormalities in gastrointestinal cancers, including research into colon cancer suppressor genes and oncogenes, functions of positive and negative growth regulatory factors and development of DNA biomarkers for early cancer detection, along with also development of new therapeutics for tissue regeneration.
Dr. Markowitz has over 200 publications and 70,000 citations, including papers published in leading journals such as Science, Science Translational Medicine, the New England Journal of Medicine, Nature, Nature Biotechnology, and Nature Genetics. He holds over 39 awarded patents.
Dr. Markowitz has been elected to the American Society of Clinical Investigation and the Association of American Physicians. He has served on the Board of Scientific Counselors of the National Cancer Institute and as a member of the scientific advisory boards of the National Colon Cancer Research Alliance (founded by Ms. Katie Couric), the Dana Farber/Harvard Cancer Center, and the Abramson Family Cancer Research Center of the University of Pennsylvania. He currently serves on the scientific advisory board of the Human Oncology and Pathogenesis Program at Memorial Sloan-Kettering Cancer Center.
Dr. Markowitz’s additional recognitions include past service as head of the Cancer Genetics Program at the Case Comprehensive Cancer Center, as Principal Investigator of the Case GI Cancers SPORE, a National Cancer Institute-designated program of research excellence in gastrointestinal cancers and being an alumnus investigator of the Howard Hughes Medical Institute.
Dr. Markowitz earned a bachelor’s degree in chemistry and physics from Harvard University, Cambridge, MA, and his MD and PhD from Yale University, New Haven, CT. He served a fellowship in medical oncology at the National Cancer Institute, Bethesda, MD.
Research & Publications
Research Interests
Molecular Genetics of Colon Cancer, Molecular Differences in Colon Cancers in Different Ethnic Populations, Molecular Biology of Cancer Metastases, Molecular Tests for Early Detection of Cancers and Pre-Cancers in the Colon and the Esophagus, Genetic Tests for Determining Cancer Risks, Personalized Genetic Tests for Cancer Prevention, Oncogenes and Suppressor Genes in Human Cancer, Developing Drugs for Cancer Prevention, Developing Drugs for Tissue Regeneration and Repair after Bone Marrow Transplantation, Cancer Surgery, or Injury from Colitis