Joseph Khouri, MD

About

Joseph S. Khouri, MD, is an Associate Professor in the Department of Plastic and Reconstructive Surgery at University Hospitals Cleveland Medical Center and Case Western Reserve University School of Medicine. Dr. Khouri’s clinical expertise focuses on microvascular surgery, complex upper and lower extremity reconstruction, nerve repair and breast reconstruction. He is widely recognized for his work in targeted nipple reinnervation, nipple areola preservation and direct-to-implant (DTI) breast reconstruction, as well as targeted muscle reinnervation (TMR) to manage chronic pain and improve outcomes for amputees.

Dr. Khouri was born and raised in Cleveland, Ohio, where his path to medicine was deeply personal. At age seven, he was critically injured and ejected from a vehicle during a major car accident on a Cleveland freeway. After being “put back together” by reconstructive surgeons, he developed a lifelong admiration for the technical skill and compassion required to heal patients from the “outside-in.” Before his medical career, Dr. Khouri also gained unique perspective as a small business owner in the restaurant industry, where he embraced the philosophy of “servant-leadership” and honed a sophisticated bedside manner grounded in empathy.

An accomplished academic, Dr. Khouri earned his undergraduate degree in economics from the University of Michigan before receiving his medical doctorate from Wayne State University School of Medicine. He completed a plastic surgery residency at the University of Rochester Medical Center and a prestigious microvascular surgery fellowship at the Mayo Clinic. Enhancing his leadership and operational expertise, he also achieved an Executive MBA from the Case Western Reserve Weatherhead School of Management.

Throughout his career, Dr. Khouri has been a prolific contributor to medical literature, authoring numerous peer-reviewed publications and book chapters on advanced microsurgical techniques and reconstructive outcomes. He is a sought-after national speaker and a member of the American Society of Plastic Surgeons and the Ohio Valley Society of Plastic Surgery.

Outside of his surgical practice, Dr. Khouri is a dedicated family man who enjoys spending time in Cleveland with his wife and three children. Whether traveling for family vacations or attending to his community, his primary passion remains grounded in the meaningful relationships he builds both at home and with those he serves.