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Jeffrey Hardacre, MD

Jeffrey Hardacre, MD



50 Ratings 15 Reviews


Surgical Oncology, General Surgery

Accepting New Patients

Primary Location

UH Cleveland Medical Center
11100 Euclid Ave
Cleveland, OH 44106

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  • Chair, Surgical Oncology Quality Committee, UH Cleveland Medical Center
  • Professor, CWRU School of Medicine

Jeffrey M. Hardacre, MD, FACS, is a surgeon in the University Hospitals Seidman Cancer Center. He sees patients at UH Cleveland Medical Center in Cleveland, Ohio, and UH Chagrin Highlands Health Center in Orange, Ohio. He operates at UH Cleveland Medical Center. Dr. Hardacre is a Professor of Surgery at Case Western Reserve University School of Medicine.

Dr. Hardacre is board certified in surgery. His clinical interests include cancers of the pancreas, stomach, bile duct, gallbladder and intestine. He also provides surgical care for benign diseases of the pancreas, including cysts and pancreatitis, and performs abdominal general surgery. Dr. Hardacre was named to the UH Seidman Cancer Center medical staff in 2004.

Dr. Hardacre earned his undergraduate degree in molecular biology from the University of Wisconsin-Madison, where he was elected to Phi Beta Kappa, and his Doctor of Medicine degree from Duke University School of Medicine in Durham, North Carolina, where he was elected to Alpha Omega Alpha. He completed his residency in general surgery and a surgical research fellowship at The Johns Hopkins Hospital in Baltimore, Maryland. He also completed advanced specialty training in gastrointestinal surgery at Johns Hopkins.

An active researcher, Dr. Hardacre is principal investigator at UH of a study examining a novel drug that targets mitochondria in pancreatic cancer cells. Dr. Hardacre has published more than 40 scientific papers in leading professional journals and is the author of multiple chapters in surgical textbooks. In addition, he is an active participant in national medical meetings, presenting abstracts, posters and invited lectures.

Dr. Hardacre is a fellow of the American College of Surgeons and member of the Society for Surgery of the Alimentary Tract, the Midwest Surgical Association, the Pancreas Club and the Central Surgical Association. In addition, he is a reviewer for the surgical journals Surgery, Annals of Surgery, Journal of the American College of Surgeons, and American Journal of Surgery.


  • Biliary Surgery
  • Gallbladder Surgery
  • Gastric Surgery
  • Gastrointestinal Surgery
  • Pancreatic Surgery
  • Surgical Oncology


Watch to find out more about this University Hospitals physician.

Languages Spoken


Office Locations

UH Cleveland Medical Center

11100 Euclid Ave
Cleveland OH, 44106

CMC Bolwell Ste 2100

11100 Euclid Ave
Cleveland OH, 44106

UH Minoff Health Center at Chagrin Highlands

3909 Orange Pl
Beachwood OH, 44122

St John Med Ctr Bldg 3 Ste 340

29099 Health Campus Dr
Westlake OH, 44145

UH Seidman Cancer Center

29325 Health Campus Dr
Westlake OH, 44145

UH Sharon Health Center

5133 Ridge Rd
Wadsworth OH, 44281

Patient Experience Reviews

4.8 out of 5

50 Ratings

Patient Comments (15)

Reviewed On 2/1/2023
Wonderful doctor and staff. Highly recommend him. Always happy and cheerful.

Reviewed On 2/1/2023
Dr Hardacre has a great bedside manner and is a very knowledgeable doctor.

Reviewed On 2/1/2023
Wonderful experience with this doctor. Probably best doctor experience I've ever had. He talked about my condition, let me talk about my condition and we came up with a solid plan.

Reviewed On 12/1/2022
Dr Hardacre is a excellent provider. He gives great information and answers all questions. From the first time I met him he has made my experience positive with something that could be very scary.

Reviewed On 11/1/2022
Excellent waiting! Dr Hardacre explains everything completely and has great bedside manner! His staff reflects him . Personable and helpful! A+ To everyone!!!!

Reviewed On 11/1/2022
Dr Hardacre is excellent. I moved away from Ohio but still go to see him every year for my problem. If I end up needing surgery, I would want him to perform it.

Reviewed On 11/1/2022
I would recommend Dr Hardacre to anyone great Dr compassionate and caring hard to find now days

Reviewed On 10/1/2022
This doctor was phenomenal!

Reviewed On 9/2/2022
Dr. Hardacre is an amazing doctor, extremely knowledgeable, upfront, informative and caring. He is the type of doctor that other doctors should strive to become, he is humble, and knows how to maneuver difficult topics.

Reviewed On 9/2/2022
Jeff was very personable and knowledgeable. We had a good rapport immediately, and bonded over a shared love of music. It's great to see a provider that can be a human being as well as a physician.

Reviewed On 9/2/2022

Reviewed On 7/1/2022
Dr. Hardacre is an extremely knowledgeable, professional, caring provider. He was able to relate statistics about 80-year-old patients who were diagnosed with pancreatic cancer. Was also able to help me see some of the options that might be available to me with somewhat limited life expectancy. Explained that there were no cures available for an 80-year-old woman. I greatly appreciated his honesty and his ability to prepare me for the options that I might be given based on another blood test and another CT Scan. Would highly recommend this doctor. His compassionate nature and overall knowledge about someone with my medical problems were truly outstanding.

Reviewed On 7/1/2022
Everyone was so nice and professional. Dr hard acre was very caring and informative and seems to go the extra mile. At this point I would recommend.

Reviewed On 5/1/2022
Excellent surgeon and wonderful uplifting demeanor!

Reviewed On 4/1/2022
Great firat time contact. He really defined the condition and what needs to happen next.

Certifications & Memberships

  • Surgery - American Board of Surgery


Fellowship | Endoscopy - Advanced
Endoscopy - Advanced - Cleveland Clinic (2003 - 2004)

Fellowship | Gastrointestinal Surgery
Gastrointestinal Surgery - Johns Hopkins University (2002 - 2003)

Residency | General Surgery
General Surgery - Johns Hopkins Hospital (1996 - 2002)

Medical Education
Duke University School Of Medicine (1992 - 1996)

University Of Wisconsin-Madison (1992)

Industry Relationships

University Hospitals is committed to transparency in our interactions with industry partners, such as pharmaceutical, biotech, or medical device companies. At UH, we disclose practitioner and their family members’ ownership and intellectual property rights that are or in the process of being commercialized. In addition, we disclose payments to employed practitioners of $5,000 or more from companies with which the practitioners interact as part of their professional activities. These practitioner-industry relationships assist in developing new drugs, devices and therapies and in providing medical education aimed at improving quality of care and enhancing clinical outcomes. At the same time, UH understands that these relationships may create a conflict of interest. In providing this information, UH desires to assist patients in talking with their practitioners about industry relationships and how those relationships may impact their medical care.

UH practitioners seek advance approval for certain new industry relationships. In addition, practitioners report their industry relationships and activities, as well as those of their immediate family members, to the UH Office of Outside Interests annually. We review these reports and implement management plans, as appropriate, to address conflicts of interest that may arise in connection with medical research, clinical care and purchasing decisions.

View UH’s policy (PDF) on practitioner-industry relationships.

As of December 31, 2016, Jeffrey Hardacre did not disclose any Outside Relationships with Industry.