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Brian Appleby, MD

Brian Appleby, MD

  • Specialty: Psychiatry, Neurology, Psychiatry-Geriatric Psychiatry
    View Expertise
  • Primary Location: 3619 Park East Dr Ste 109 (7 mi.)
    Other Locations
  • Languages Spoken: English

Office Locations

UH Foley ElderHealth Center (7 mi.)

3619 Park East Dr
Ste 109
Beachwood, OH 44122

216-464-6445

UH Cleveland Medical Center Lakeside Building 65 (0 mi.)

11100 Euclid Ave
Cleveland, OH 44106
216-844-4900

UH Foley ElderHealth Center (7 mi.)

3619 Park East Dr
Ste 211
Beachwood, OH 44122
216-464-6215

Biography: Brian Appleby, MD

Expertise

  • Behavioral Neurology
  • Creutzfeldt-Jakob Disease
  • Dementia
  • Neuropsychiatry
  • Prion Diseases
  • Young-Onset Dementia

Titles

  • Associate Professor of Psychiatry, CWRU School of Medicine
  • Professor of Neurology, CWRU School of Medicine
  • Professor of Psychiatry, CWRU School of Medicine

Certifications & Memberships

  • Geriatric Psychiatry - American Board of Psychiatry and Neurology
  • Psychiatry - American Board of Psychiatry and Neurology
  • Certification in Behavioral Neurology & Neuropsychiatry, United Council for Neurologic Subspecialties

Education

Fellowship | Geriatric Psychiatry
Geriatric Psychiatry - THE JOHNS HOPKINS HOSPITAL (2007 - 2008)

Residency | Psychiatry
Psychiatry - THE JOHNS HOPKINS HOSPITAL (2004 - 2007)

Internship | Psychiatry
Psychiatry - Georgetown University Hospital (2003 - 2004)

Medical Education
Georgetown University School Of Medicine (2003)

Undergraduate
Goucher College (1999)

About

Brian Appleby, MD is a neuropsychiatrist at University Hospitals Cleveland Medical Center who treats and researches cognitive disorders. Dr. Appleby is an associate professor of neurology, psychiatry, and pathology at Case Western Reserve University and University Hospitals Cleveland Medical Center, the National Prion Disease Pathology Surveillance Center Director, and Medical Director of the Creutzfeldt-Jakob (CJD) Foundation. He is also chair of the Cleveland Chapter Alzheimer's Association Professional Advisory Board.  

Dr. Appleby received his medical degree from Georgetown University School of Medicine. He completed a psychiatry residency at The Johns Hopkins Hospital, where he also completed a geriatric psychiatry fellowship.

His clinical and research interests include prion diseases (e.g., Creutzfeldt-Jakob disease), frontotemporal lobar degeneration, and young-onset dementias.

 In his free time, he enjoys spending time with his family, computers, reading, Taekwondo, and Judo.

Research & Publications

Research Interests

Prion Disease, Frontotemporal lobar degeneration, Dementia

Featured Videos

Patient Experience Reviews

5.0 out of 5
- based on 38 Ratings
(5)
7/1/2026

Dr. Appleby is a wonderful with his patients as well as highly skilled in his practice. I will always be thankful that I was referred to him. He is the doctor who correctly diagnosed me with *** and followed me thru by recommending physical therapy which kept surgery at bay for a long time but then I had the surgery that he explained and encouraged. He never pushed me into having the surgery but respected my wishes to wait. I have had surgery and it has given me my life back and I will always be grateful that I was under his care.

(5)
3/1/2026

Dr. Appleby is excellent.

(5)
3/1/2026

It was a very interesting interview with Dr. Applebey and his staff

(5)
2/1/2026

Dr Appleby has a very calm demeanor and really listened to all of our concerns. Helped us to understand the journey we have ahead of us. So glad he is on our team.

(5)
2/1/2026

The doctor is top shelf. ***

(5)
2/1/2026

Dr. Appleby was very attentive, as was his resident.

(5)
2/1/2026

Dr. Appleby and his staff were courteous and knowledgeable and quite observant and patient with my dad. Their attention to details and all input was appreciated beyond measure.

(5)
1/2/2026

Care provider was patient and supportive.

(5)
1/2/2026

Dr Appleby is the absolute best! End of conversation.

(5)
12/1/2025

Good

(5)
9/2/2025

He was pleasant. Reviewed my medical records. Ran through his exam and concluded with his assessment and plan for the future.

(5)
9/2/2025

Great!

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