Esophageal Disease

What is Eosinophilic Esophagitis?

Eosinophilic esophagitis (EoE) is a chronic immune disease that is caused by the buildup of eosinophils – a certain type of white blood cell – in the lining of the esophagus. This overproduction of eosinophils can be caused by an allergic response by the body to certain foods or other allergens or by acid reflux disease. Untreated, EoE can cause damage and inflammation that can lead to scarring and narrowing of the esophagus. The retching that is sometimes associated with food being stuck in the throat, may also lead to tears or perforations in the esophagus.


Your health is important. Don’t delay care.

To schedule an in-person or virtual consultation with a UH digestive health specialist, call 1-866-UH4-CARE.

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Eosinophilic esophagitis can occur in adults and children. In adults, the most common symptoms include:

  • Difficulty swallowing solid and liquid foods
  • Food getting stuck in the esophagus
  • Intermittent chest pain that can range from mild to intense
  • Stomach pain
  • Bitter taste due to undigested food backing up into the mouth
  • Heartburn

Risk factors for Eosinophilic Esophagitis (EoE)

Studies suggest that as the incidence of allergies and asthma grows, cases of eosinophilic esophagitis are becoming increasingly common. This means that people with food or environmental allergies or asthma, may be at greater risk for developing EoE, particularly during the spring and fall when pollen and other allergen levels are high. Additional risk factors may include:

  • Living in a cold dry climate
  • Gender – Eosinophilic esophagitis is more common in men than women
  • Family history – If someone in your family has eosinophilic esophagitis, you may have a greater chance of getting it as well

Advanced Diagnostic Testing for Eosinophilic Esophagitis

If your symptoms suggest you may have eosinophilic esophagitis, your UH esophagus specialist may perform a variety of tests to confirm the diagnosis and look for what allergens may be causing the condition. He or she will also try to determine if you have gastroesophageal reflux disease (GERD) which can be a contributing factor to EoE.

You may be prescribed one or more of the following tests:

UH Esophagus Specialists Offer Advanced Treatments for EoE

Most people diagnosed with eosinophilic esophagitis will require ongoing treatment to manage their disease and its symptoms. Treatments may include:

Your health is important. Don’t delay care.

To schedule an in-person or virtual consultation with a UH digestive health specialist, call 1-866-UH4-CARE.