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THRIVE HPV Study

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Prospective studies of vaginal mucosal systems and the microbiome in cervical cancer and HPV infection

  • Sex: Female
  • Age: Adult (18 - 64), Older Adult (65+)
  • Accepting Healthy People: No
  • Type: Correlative
  • Trial Phase: NA
  • Conditions Being Studied:

Study Purpose

The purpose of this study is to understand how differences in the vaginal microenvironment affect the progression of cervical neoplasia in women infected with the human papilloma virus (HPV). Participants will attend regular clinical sample collection visits approximately every 6 months for 3 years for a total of 7 visits. In addition, participants will complete questionnaires, an online food record tool to collect dietary information prior to the clinical visits, and provide various biosample collections.

Who Can Participate

Participants 18 years old and older with a recent abnormal PAP test or HPV may be eligible for this study.

Principal Investigator
Stefanie Avril MD
Department/Division
Pathology/Lab Medicine (Clinical Pathology)

Locations

UH Cleveland Medical Center
11100 Euclid Avenue
Cleveland OH, 44106

UH Rainbow Babies & Children’s Ahuja Center for Women & Children
5805 Euclid Avenue
Cleveland OH, 44103

  • UH IRB: STUDY20211043
  • StudyID: 2022-01083
  • ClinicalTrials.gov: N/A
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