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S-Nitrosylation Therapy Study for COVID-19

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Proof of Concept Safety Trial for S-Nitrosylation Therapy to Improve Oxygenation Status in Severe Covid-19 Patients Receiving Supplemental Oxygen Support

  • Sex: Any
  • Age: Adult (18 - 64), Older Adult (65+)
  • Accepting Healthy People: No
  • Type: Interventional / Therapeutic
  • Trial Phase: Phase I
  • Conditions Being Studied: Other Respiratory and Intrathoracic Organs, COVID-19

Study Purpose

ENO treatment has the potential to significantly improve the clinical management of patients with COVID-19 who are experiencing lung injury. In sum, ENO is a novel drug and its inhalation constitutes a unique therapeutic approach that has the potential to provide distinctive benefits to COVID-19 patients.

Principal Investigator
Robert Schilz DO
Department/Division
Medicine (Pulmonary and Critical Care Medicine)
  • UH IRB: STUDY20210599
  • StudyID: 2021-0744
  • ClinicalTrials.gov: NCT04528771
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