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Nephroureterectomy with and without Lymph Node Dissection for Upper Tract Urothelial Cell Carcinoma

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Randomized-Controlled Trial Examining Oncologic and Perioperative Outcomes for Nephroureterectomy with and without Lymph Node Dissection for Upper Tract Urothelial Cell Carcinoma

  • Sex: Any
  • Age: Adult (18 - 64), Older Adult (65+)
  • Accepting Healthy People: No
  • Type: Observational
  • Trial Phase: NA
  • Conditions Being Studied:

Study Purpose

The purpose of this research study is to determine if removing the lymph nodes at time of nephroureterectomy provides better cancer control. The reason that lymph node dissection with nephroureterectomy might provide better cancer control is that the lymph nodes in the region of the tumor are often where the cancer spreads if it does spread outside of the kidney and/or ureter.

Who Can Participate

Men and women 18 or older that have been diagnosed with Upper Tract Urothelial Cell Carcinoma, and have a nephroureterectomy planned may be eligible for this study.

Principal Investigator
Adam Calaway MD MPH
Department/Division
Urology (Urologic Oncology)

Locations

UH Geauga Medical Center
13207 Ravenna Road
Chardon OH, 44024

UH Ahuja Medical Center
3999 Richmond Road
Beachwood OH, 44122

UH Parma Medical Center
7007 Powers Boulevard
Parma OH, 44129

UH St. John Medical Center
29000 Center Ridge Road
Westlake OH, 44145

  • UH IRB: N/A
  • StudyID: 2024-01491
  • ClinicalTrials.gov: NCT06262516
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