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NanO2TM Combined With Radiation and Temozolomide in Glioblastoma (RESTORE)

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A phase 2 double-blind, RandomizEd, prospective, placebo controlled STudy of NanO2 TM combined with Radiation and temozolomide in patients with newly-diagnosed glioblastoma multiformE: RESTORE

  • Sex: Female
  • Age: Adult (18 - 64), Older Adult (65+)
  • Accepting Healthy People: No
  • Type: Interventional / Therapeutic
  • Trial Phase: Phase I
  • Conditions Being Studied: Cancer - Brain and Nervous System

Study Purpose

This clinical trial is testing the safety and efficacy of NanO2TM administered via intravenous infusion in combination with standard radiation and chemotherapy. NanO2TM is being developed to increase the amount of oxygen delivered to tumors which is hoped to increase the effectiveness of radiation therapy.

Principal Investigator
Herbert Newton MD
Department/Division
Cancer (Brain and Central Nervous System)
  • UH IRB: STUDY20240082
  • StudyID: NVOX1323
  • ClinicalTrials.gov: NCT03862430
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