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A Randomized, Double-blind, Placebo-controlled Phase 4 Clinical Trial to Evaluate the Long-term Safety and Efficacy of Avacopan in Subjects with Antineutrophil Cytoplasmic Antibody (ANCA)-associated Vasculitis

Sex: Any
Age: Adult (18 - 64), Older Adult (65+)
Accepting Healthy People: No
Type: Interventional / Therapeutic
Trial Phase: Phase IV
Conditions Being Studied: Antineutrophil Cytoplasmic Antibody (ANCA)-associated Vasculitis

Study Purpose

This study is being done to learn more about the good or bad effects of avacopan and how well it is working in treatment of ANCA-associated vasculitis. Additionally, the study also aims to assess the maintenance of remission (recovery state) on treatment with avacopan in participants confirmed with ANCA-associated vasculitis.

Who Can Participate

Age: 18 and older

Principal Investigator
Andrew Lazar MD

Department/Division
Medicine (Nephrology)

Locations

UH Cleveland Medical Center
11100 Euclid Ave
Cleveland OH, 44106

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UH IRB: STUDY20231420
StudyID: 2023-01359
ClinicalTrials.gov: NCT06072482

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