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DOSA Trial

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Randomized Control Trial of Oxygen Therapy in Children and Adolescents with Down Syndrome and Obstructive Sleep Apnea

  • Sex: Any
  • Age: Child (Birth - 17)
  • Accepting Healthy People: No
  • Type: Interventional / Therapeutic
  • Trial Phase: NA
  • Conditions Being Studied: Obstructive Sleep Apnea, Downs Syndrome

Study Purpose

The purpose of this study is to assess whether oxygen supplementation during sleep improves cognitive functioning such as working memory among children who have Down syndrome with moderate to severe obstructive sleep apnea (OSA).

Who Can Participate

Participants 5-17.9 years of age with Down syndrome and diagnosed with OSA after having the typical surgery for OSA in children (adenotonsillectomy) may be eligible for this study. For more information about this trial visit https://www.dosatrial.org/

Principal Investigator
Sally Ibrahim MD
Department/Division
Pediatrics (Pulmonology)

Locations

UH Rainbow Babies & Children's
2101 Adelbert Road
Cleveland OH, 44106

UH Cleveland Medical Center
11100 Euclid Avenue
Cleveland OH, 44106

  • UH IRB: SITE00002057
  • StudyID: 2023-01315
  • ClinicalTrials.gov: NCT06043440
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