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De-Escalation of Breast Radiation for HER-2 Negative Breast Cancer, Oncotype Recurrence Score </= 18

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A Phase III Clinical Trial Evaluating De-Escalation of Breast Radiation for Conservative Treatment of Stage I, Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer

  • Sex: Female
  • Age: Adult (18 - 64), Older Adult (65+)
  • Accepting Healthy People: No
  • Type: Interventional / Therapeutic
  • Trial Phase: Phase I
  • Conditions Being Studied: Cancer - Breast

Study Purpose

This Phase III Trial evaluates whether breast conservation surgery and endocrine therapy results in a non-inferior rate of invasive or non-invasive ipsilateral breast tumor recurrence (IBTR) compared to breast conservation with breast radiation and endocrine therapy.

Principal Investigator
Janice Lyons MD
Department/Division
Cancer (Breast)
  • UH IRB: CIRB; 21-1060
  • StudyID: NRG-BR007
  • ClinicalTrials.gov: NCT04852887
I'm Interested!
Please call
1-800-641-2422

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