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CAPTIVA Therapies Study for Intracranial Vascular Atherostenosis

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Comparison of Anti-coagulation and anti-Platelet Therapies for Intracranial Vascular Atherostenosis

  • Sex: Any
  • Age: Adult (18 - 64), Older Adult (65+)
  • Accepting Healthy People: No
  • Type: Interventional / Therapeutic
  • Trial Phase: Phase III
  • Conditions Being Studied: Brain and Nervous System, Stroke

Study Purpose

The purpose of this research study is to see whether ticagrelor and aspirin or rivaroxaban and aspirin compared to clopidogrel and aspirin will have the most success in preventing another stroke, bleed in the brain, or death in participants who have already had a stroke from a narrowed brain artery.

Who Can Participate

Age: 30-80 years old

Principal Investigator
Sepideh Amin-Hanjani MD
Department/Division
Neurology (Stroke)

Locations

UH Cleveland Medical Center
11100 Euclid Ave
Cleveland OH, 44106

UH Ahuja Medical Center
3999 Richmond Rd
Beachwood OH, 44122

University Hospitals Mentor Health Center
9485 Mentor Ave
Mentor OH, 44060

UH Minoff Health Center at Chagrin Highlands
3909 Orange Pl
Orange Village OH, 44122

UH Westlake Health Center
960 Clague Rd
Westlake OH, 44145

  • UH IRB: STUDY20221498
  • StudyID: 2022-01085
  • ClinicalTrials.gov: NCT05047172
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