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BARRIGEL

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Randomized trial of Barrigel to increase distance between the rectum and prostate bed to decrease rectal dose in patients receiving moderately hypofractionated radiation therapy who had recurrence of prostate cancer after prostatectomy

  • Sex: Male
  • Age: Adult (18 - 64)
  • Accepting Healthy People: No
  • Type: Interventional / Device
  • Trial Phase: Phase IV/V
  • Conditions Being Studied: Cancer - Prostate

Study Purpose

The purpose of this research is to determine if Barrigel is safe and effective (works well) when it is injected between the prostate bed and rectum to create space. The prostate bed is the location where your prostate was located previously to it being removed. This space may reduce the radiation dose and side effects to the rectum during radiation therapy treatment for prostate cancer that recurs after the prostate has been removed.

Who Can Participate

Age = 18 years

Principal Investigator
Jonathan Shoag MD
Department/Division
Urology (Urologic Oncology)

Locations

UH Cleveland Medical Center
11100 Euclid Ave
Cleveland OH, 44106

UH Seidman Cancer Center
11100 Euclid Ave
Cleveland OH, 44106

UH Ahuja Medical Center
3999 Richmond Rd
Beachwood OH, 44122

UH Beachwood Medical Center
25501 Chagrin Blvd
Beachwood OH, 44122

UH Parma Medical Center
7007 Powers Blvd
Parma OH, 44129

UH Otis Moss Jr. Health Center
8819 Quincy Ave
Cleveland OH, 44106

UH Suburban Health Center
1611 S Green Rd
South Euclid OH, 44121

  • UH IRB: STUDY20250464
  • StudyID: 2025-01659
  • ClinicalTrials.gov: NCT06496256
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