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ARX517/JNJ-95298177 as Monotherapy or Combo Therapy in Metastatic Prostate Cancer (ARX517)

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A Phase 1, Multicenter, Open-Label, Dose-Escalation, and Dose-Expansion Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of ARX517 as Monotherapy and in Combination With Androgen Receptor Pathway Inhibitors in Subjects With Metastatic Prostate Cancer

  • Sex: Male
  • Age: Adult (18 - 64), Older Adult (65+)
  • Accepting Healthy People: No
  • Type: Interventional / Therapeutic
  • Trial Phase: Phase I
  • Conditions Being Studied: Cancer - Prostate

Study Purpose

This is a phase 1 study to assess the safety and tolerability of ARX517 as monotherapy or combination therapy in adult subjects with metastatic prostate cancer (mPC).

Principal Investigator
Pedro Barata MD
Department/Division
Cancer (Genitourinary)
  • UH IRB: STUDY20250233
  • StudyID: AMBRX1825
  • ClinicalTrials.gov: NCT04662580
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