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ADIPOSA Study

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Adipose Dysfunction, Imaging, Physiology, and Outcomes With SGLT2i's for Sleep Apnea: The ADIPOSA Study

  • Sex: Any
  • Age: Adult (18 - 64), Older Adult (65+)
  • Accepting Healthy People: No
  • Type: Interventional / Therapeutic
  • Trial Phase: NA
  • Conditions Being Studied: Obstructive Sleep Apnea

Study Purpose

The purpose of the study is to evaluate the effectiveness of an investigative medication, bexagliflozin, for obstructive sleep apnea (OSA). Study Details The study participation will last approximately six months with five visits to the hospital. These visits will take about 12-hours total. Study procedures will include sleep studies, questionnaires, two MRI scans, wearing an activity tracker, blood pressure monitoring, and laboratory tests.

Who Can Participate

Participants 18 years and older that are overweight or obese (body mass index 25-40 kg/m2) and have a clinically confirmed diagnosis of obstructive sleep apnea may be eligible for this study.

Principal Investigator
Ian Neeland MD
Department/Division
Heart and Vascular (Translational Sciences)

Locations

UH Cleveland Medical Center
11100 Euclid Avenue
Cleveland OH, 44106

  • UH IRB: STUDY20221063
  • StudyID: 2022-01088
  • ClinicalTrials.gov: NCT05612594
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