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A Phase 1 Dose Escalation and Expansion Study of ZG006 in Patients With Small Cell Lung Cancer

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A Phase 1 Dose Escalation Study of the Tolerability, Safety, Efficacy and Pharmacokinetics of ZG006 in Patients With Small Cell Lung Cancer

  • Sex: Any
  • Age: Adult (18 - 64), Older Adult (65+)
  • Accepting Healthy People: No
  • Type: Interventional / Therapeutic
  • Trial Phase: Phase I
  • Conditions Being Studied: Cancer - Lung

Study Purpose

This is a multi-center, open-label, Phase 1 clinical study of ZG006 in the US for the treatment of subjects with small cell lung cancer who have failed or are intolerant to available standard treatment. During the dose escalation stage, a standard "3+3" design will be used to assess the MTD/ recommended dose for the subsequent studies.

Principal Investigator
Afshin Dowlati MD
Department/Division
Cancer (Thoracic)
  • UH IRB: STUDY20251237
  • StudyID: SUZH1525
  • ClinicalTrials.gov: NCT06592638
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