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HIKO STEC Study

Hyperhydration to Improve Kidney Outcomes in Children with Shiga Toxin-Producing E. coli Infection: A Multinational Embedded Cluster Crossover Randomized Trial

kidney illustration
AGE: 9 months to < 21 years old
Healthy Participants: No
TYPE: Multicenter, Cluster-Randomized, Crossover Trial
CONDITION: Shiga Toxin-Producing Escherichia Coli (STEC) Infection, Early Hemolytic Uremic Syndrome (HUS)
LOCATION: UH Rainbow Babies and Children’s Hospital and Rainbow Primary Care Institute Practices

Learn More About This Research Study

To learn more about this study, please contact study coordinators, SaTia Sinclair and Kimberly Myers, at 440-340-3413 or complete the online form below.

Study Purpose

The purpose of this study is to determine if early high volume intravenous fluid administration (hyperhydration) to children diagnosed with STEC infection improves kidney and other clinical outcomes when compared with a conservative fluid management approach.

Who Can Participate

Participants 9 months to < 21 years old with a diagnosis of STEC infection or early HUS may be eligible for this study.

Request More Information

If you are the parent or guardian of a child who may be eligible for this research study and you want to learn more about participating, please fill out the form below to request more information.

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