Neurological & Behavioral Outcomes Center

Neurological & Behavioral Outcomes Center Maintains Commitment to Continuous Improvement

The mission of the Neurological & Behavioral Outcomes Center (NOC) at University Hospitals Neurological Institute in Cleveland, Ohio is “to identify, develop and assist with implementing methods and approaches and creating new knowledge in patient care, education, and research that deliver the highest value health care as defined by improved outcomes in patients with neurological conditions.”

The NOC was established in 2009 and is a collaborative effort between University Hospitals Neurological Institute and Case Western Reserve University School of Medicine. It is supported in part by a Clinical and Translational Science Award (CTSA) given to Case Western Reserve University School of Medicine. The CTSA funds a national consortium of medical research institutions to improve the way biomedical research is conducted across the U.S.

The NOC team is devoted to studying outcomes for patients with neurological and neuropsychiatric conditions, and since its inception, NOC has developed a reputation for novel methodologies and for health promotion approaches that have the potential to advance health outcomes for patients and families. Ongoing projects are focusing on improving self-management in people with Parkinson’s disease and stroke, and the NOC team has recently initiated programs in epilepsy self-management. Other areas of interest include assessment methods in neurodegenerative illness and refinement of functional neuro-imaging methods that optimize the efficient use of technology and neurological assessments.

NOC combines the expertise of leading specialists from a variety of disciplines, including neurology, psychiatry, epidemiology, biostatistics, and the social and basic sciences, who work together to develop innovative approaches to outcomes research in neurology. The center also focuses on generating new research ideas and helping investigators shape their ideas into proposals and grant applications.

Significant Contributions to Neuroscience

The Neurological & Behavioral Outcomes Center (NOC) is designed to generate new research and to help investigators shape their ideas into proposals and grant applications. Working with investigators from University Hospitals Neurological Institute (NI), Case Western Reserve University (CWRU) School of Medicine and the CWRU School of Nursing, as well as from a variety of other local, regional and national research groups, NOC researchers have lead and/or collaborated on projects intended to advance care in neuroscience. Recognizing the critical importance of preliminary data to continue a robust research trajectory, NOC is also involved in pilot projects intended to support the submission of future grant applications, and to lead to improvements in UH Neurological Institute clinical programming.

Research application and grant funding highlights:

  • In 2011, NOC investigators participated in 23 new research grant applications and received $3.453 million in new research funding.
  • In the first half of 2012, NOC investigators participated in five new research grant applications, and received $3.086 million in new federally funded research grants, $110,000 in foundation-funded research grants and $8,000 in industry-funded grants.

Publications and Presentations

NOC is developing a reputation for novel methodologies and for health promotion approaches that have the potential to advance health outcomes for patients and families. This is demonstrated by a robust publication and presentation track record. NOC is also committed to training and developing the next generation of researchers. NOC faculty participate in mentoring, training and career development activities with trainees, faculty, and staff across a wide variety of disciplines and topic areas.

Publication and knowledge dissemination highlights:

  • NOC investigators had 22 new papers, books/book chapters or editorials published or in press between January and June 2012.
  • NOC investigators present at local, regional and national scientific meetings, and contribute to late-breaking research reports and CME programs.

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