TOPAZ
A Randomized Placebo-controlled Trial of Zoledronic Acid for Prevention of Fractures in Patients with Parkinson’s Disease
- Sex at Birth: Any
- Age: Adult (18 - 64), Older Adult (65+)
- Accepting Healthy People: No
- Type: Interventional / Therapeutic
- Trial Phase: NA
- Conditions Being Studied: Brain and Nervous System, Parkinsons Disease
Study Purpose
The purpose of this at-home study is to test the efficacy of zoledronic acid (ZA) in Parkinson's disease (PD) and parkinsonism patients. This trial will also address barriers to treatment of patients with PD and parkinsonism by providing rigorous evidence about whether ZA reduces fracture risk in patients with PD and parkinsonism.
Who Can Participate
Age: 60 and older
Locations
UH Minoff Health Center at Chagrin Highlands
3909 Orange Place
Orange Village OH, 44122
UH Suburban Health Center
1611 South Green Road
South Euclid OH, 44121
UH Cleveland Medical Center
11100 Euclid Avenue
Cleveland OH, 44106
- UH IRB: SITE00001453
- StudyID: 2021-0556
- ClinicalTrials.gov: NCT03924414
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