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Skin Biopsy

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Premortem detection of misfolded proteins in biopsy skin samples, subcutaneous fat, saliva and hairs of patients with various neurodegenerative diseases

  • Sex at Birth: Any
  • Age: Adult (18 - 64), Older Adult (65+)
  • Accepting Healthy People: Yes
  • Type: Tissue Banking or Laboratory Collection
  • Trial Phase: Phase I
  • Conditions Being Studied: Parkinsons Disease

Study Purpose

The purpose is to determine if our skin alpha-synuclein assay will differentiate Parkinson's disease, multiple system atrophy, and dementia with Lewy bodies from tauopathies progressive supranuclear palsy and corticobasal syndrome and controls. The objective is to develop a skin test for PD and parkinsonism.

Principal Investigator
Steven Gunzler MD
Department/Division
Movement Disorders (Neurology)

Locations

UH Foley ElderHealth Center
3619 Park East Drive
Beachwood OH, 44122

UH Suburban Health Center
1611 South Green Road
South Euclid OH, 44121

UH Cleveland Medical Center
11100 Euclid Avenue
Cleveland OH, 44106

  • UH IRB: STUDY20181189
  • StudyID: STUDY20181189
  • ClinicalTrials.gov: NCT04518059
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