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Site for Reliance COPD Exacerbations stage 2

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RofLumilast or Azithromycin to Prevent COPD Exacerbations (RELIANCE)

  • Sex at Birth: Any
  • Age: Adult (18 - 64), Older Adult (65+)
  • Accepting Healthy People: No
  • Type: Interventional / Therapeutic
  • Trial Phase: Phase III
  • Conditions Being Studied: Chronic Obstructive Pulmonary Disease (COPD)

Study Purpose

RELIANCE is a study comparing two drugs. We are trying to learn which one works better, and is better tolerated in people with Chronic Obstructive Pulmonary Disease (COPD). COPD is a lung disease. We want to compare these drugs in a real world setting.Today, doctors use both Roflumilast and Azithromycin to treat COPD. Research shows that people who take Roflumilast or Azithromycin go to the hospital less often for COPD attacks. We want to see if Azithromycin is as good as Roflumilast for preventing COPD attacks and thereby decrease hospital visits.

Who Can Participate

Age: 40 and older

Principal Investigator
Catalina Teba MD
Department/Division
Pulmonary and Critical Care Medicine (Medicine)

Locations

UH Cleveland Medical Center
11100 Euclid Avenue
Cleveland OH, 44106

  • UH IRB: SITE00000081
  • StudyID: SITE00000081
  • ClinicalTrials.gov: NCT04069312
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