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Project 1 GSNO challenge

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Methods to Identify and Treat Severe Asthma Patients Project 1: GSNOR Phenotyping and GSNO Challenge

  • Sex at Birth: Any
  • Age: Adult (18 - 64)
  • Accepting Healthy People: Yes
  • Type: Interventional / Therapeutic
  • Trial Phase: Phase I
  • Conditions Being Studied: Asthma

Study Purpose

The purpose of this study is to confirm previous work demonstrating that participants with asthma have higher GSNOR activity levels than healthy volunteers, expand our ability to predict who will have elevated GSNOR activity levels based on clinical phenotype, and to develop non-invasive and point of care testing that can accurately identify those with elevated GSNOR levels.

Principal Investigator
Kristie Ross MD
Department/Division
Pulmonology (Pediatrics)

Locations

UH Cleveland Medical Center
11100 Euclid Avenue
Cleveland OH, 44106

  • UH IRB: 12-17-11
  • StudyID: 12-17-11.
  • ClinicalTrials.gov: NCT03926741
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