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PRECISE

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Site for PeRsonalizEd immunomodulation in pediatriC sepsIS-inducEd MODS

  • Sex at Birth: Any
  • Age: Child (Birth - 17)
  • Accepting Healthy People: No
  • Type: Interventional / Therapeutic
  • Trial Phase: NA
  • Conditions Being Studied: Sepsis

Study Purpose

You are being asked to take part in a research study because you have a severe infection called sepsis, which is causing two or more of your organs to work poorly. We know that when this happens, your immune function may be too low and/or the amount of inflammation in your body may be too high. We can test for these things in the research laboratory. Routine treatment for children with sepsis does not include medicine to help boost immune function or reduce inflammation. We think that if you get treated with a medicine that matches what your immune system needs (an immune boosting medicine called GM-CSF, or an anti-inflammatory medicine called anakinra, depending on your test results), you will be more likely to recover and you will recover more quickly.

Principal Investigator
Steven Shein MD
Department/Division
Critical Care (Pediatrics)

Locations

UH Cleveland Medical Center
11100 Euclid Avenue
Cleveland OH, 44106

  • UH IRB: SITE00001604
  • StudyID: 2021-0803
  • ClinicalTrials.gov: N/A
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