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C4671026

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A PHASE 2/3, INTERVENTIONAL SAFETY, PHARMACOKINETICS, AND EFFICACY, OPEN-LABEL, MULTI-CENTER, SINGLE-ARM STUDY TO INVESTIGATE ORALLY ADMINISTERED PF-07321332 (NIRMATRELVIR)/RITONAVIR IN NONHOSPITALIZED SYMPTOMATIC PEDIATRIC PARTICIPANTS WITH COVID-19 WHO ARE AT RISK OF PROGRESSION TO SEVERE DISEASE

  • Sex at Birth: Any
  • Age: Child (Birth - 17)
  • Accepting Healthy People: No
  • Type: Interventional / Therapeutic
  • Trial Phase: Phase II/III
  • Conditions Being Studied: Other Respiratory and Intrathoracic Organs, COVID-19

Study Purpose

The purpose of the study is to find out if PF-07321332 (nirmatrelvir) co-packaged with ritonavir which is the study drug, helps treat non-hospitalized symptomatic children with COVID-19 who are at risk of their COVID-19 infection getting worse.

Principal Investigator
Grace McComsey MD
Department/Division
Infectious Disease (Pediatrics)

Locations

UH Cleveland Medical Center
11100 Euclid Avenue
Cleveland OH, 44106

  • UH IRB: SITE00001690
  • StudyID: 2022-0870
  • ClinicalTrials.gov: NCT05261139
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