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Atezolizumab w or w/o Bevacizumab in Hepatocellular Carcinoma and Child-Pugh B7 and B8 Cirrhosis

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GENE 1224 (ML44719) A Phase II, Open-Label, Multi-Cohort, Multi-Center Study in Patients with un-resectable hepatocellular carcinoma and child-pugh B7 and B8 cirrhosis. GENE 1224 (ML44719)

  • Sex at Birth: Any
  • Age: Adult (18 - 64), Older Adult (65+)
  • Accepting Healthy People: No
  • Type: Interventional / Therapeutic
  • Trial Phase: Phase I
  • Conditions Being Studied: Cancer - Pancreas

Study Purpose

The purpose of this study is to assess the safety and efficacy of atezolizumab and bevacizumab, or atezolizumab alone, as first-line treatment in participants with unresectable, locally advanced or metastatic hepatocellular carcinoma (HCC) with Child-Pugh B7 or B8 cirrhosis.

Principal Investigator
Amit Mahipal MD
Department/Division
Cancer (Digestive System)

Locations

UH Seidman Cancer Center
11100 Euclid Avenue
Cleveland OH, 44106

  • UH IRB: Pro00079207
  • StudyID: GENE1224
  • ClinicalTrials.gov: NCT06096779
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