Neurosurgery Clinical Trials

Many of the neurosurgery trials that we conduct at University Hospitals enroll patients who are in the acute stage of their disease or injury. This means that patients are enrolled while they are in the emergency room, intensive care unit, or operating room. You can read about some of these trials below and at clinicaltrials.gov. For any questions about our current neurosurgery studies, please contact Mary Andrews or Gordon Williams.


PVSRIPO in Recurrent Malignant Glioma

A Multicenter Phase 2 Study of Oncolytic Polio/Rhinovirus Recombinant (PVSRIPO) in Recurrent WHO Grade IV Malignant Glioma Patients

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MIND: Artemis in the Removal of Intracerebral Hemorrhage

A Prospective, Multicenter Study of Artemis a Minimally Invasive Neuro Evacuation Device, in the Removal of Intracerebral Hemorrhage

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REACT: Prevention and treatment of vasospasm with ClazosenTan for patients with aneurysmal subarachnoid hemorrhage

A prospective, multicenter, double-blind, randomized, placebo-controlled, parallel-group, Phase 3 study to assess the efficacy and safety of clazosentan in preventing clinical deterioration due to delayed cerebral ischemia (DCI), in adult subjects with aneurysmal subarachnoid hemorrhage (aSAH)

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Reducing Stroke Risk in African American Men (TEAM 2.0)

Dr. Martha Sajatovic and Dr. Carolyn Harmon Still are conducting a randomized controlled trial that uses a psychoeducational approach to reduce the unacceptably high rates of stroke and stroke complications in African-American men. It is a person-centered, holistic intervention that takes advantage of existing strengths in African-American families and/or communities.

Participants must be:

  1. African-American men
  2. Over the age of 18; and
  3. Have had a stroke/TIA within the past 5 years.

Please contact Michaela Broadnax (216-286-4362 or Michaela.Broadnax@UHhospitals.org) if you would like more information or to refer a potential participant.

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