CAR-T Therapy

Leading-Edge CAR T-Cell Immunotherapy for Children and Adults with Cancer

CAR T Cell Immunotherapy is a new, FDA-approved cancer treatment that uses the body’s own immune system to fight cancer. University Hospitals is proud to be able to offer this leading-edge therapy for patients with certain types of cancer that have been unresponsive to other treatments.

CAR-T Therapy: How Does It Work?

CAR T-cell immunotherapy works by taking white blood cells called T-cells from a patient’s blood and modifying them in a lab, essentially reprogramming them to recognize and kill cancer cells. The T-cells are then reintroduced into the patient’s body where they locate, attach to and destroy cancer cells.

CAR T-cell therapy has shown very promising results in treating these types of cancer and is giving new hope to patients in whom other standard leukemia and lymphoma treatments – such as radiation, chemotherapy and stem cell transplant – have been unsuccessful.

Who Can Benefit from CAR T-Cell Therapy?


Adults with relapsed (came back after remission) or refractory (treatment-resistant) non-Hodgkin diffuse large B-cell lymphoma.

Children & Young Adults

Children and young adults (ages 25 and under) with relapsed or refractory acute lymphoblastic leukemia (ALL) .

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