UH R&E Quarterly Newsletter June 2021


Mukesh K. Jain, MD, FAHA

The pandemic has reminded us of the critical role healthcare workers have in public health safety and the importance of building a sustainable workforce to combat future health challenges. It is inspiring to know that when our country needs Americans to step up and help, they do! Just as our military saw an enrollment increase after 9/11, our medical and nursing schools are experiencing an influx of applications this year. AAMC reports that according to the American Medical College Applications Service, there are more than 7,500 additional applicants nationwide, an increase of nearly 17%.

University Hospitals is proud to have a long-standing commitment to teaching the next generation of the medical (graduate and undergraduate) and non-medical healthcare workforce. UH Cleveland Medical Center is the home to 84 ACGME accredited programs, 4 CODA-accredited programs, and 25+ unaccredited programs. The UH Osteopathic Consortium provides ACGME accredited training for eight programs and supports 3 CPME podiatry programs. Collectively, UH is home to 1,173 trainees. UH also supports the non-physician health professionals Advanced Practice Registered Nurses and Physician Assistants programs with the clinical placement of over 900 Advanced Practice Provider students annually.


Through collaboration with strategic partners, the UH also fulfills its commitment to undergraduate medical education. These engagements are critical as they provide a robust pipeline of physician and non-physician healthcare workers. The longest-standing relationship is with Case Western Reserve University School of Medicine (CWRU-SOM). UH serves as the dominant training program for CWRU-SOM medical students, and in the affiliation agreement signed earlier this year, that commitment to training will increase for both medical and allied health trainees.


Earlier this year, UH announced a new partnership with Northeast Ohio Medical University (NEOMED) and will serve as a teaching location for up to 24 students annually. The collaboration aligns with the goals of both institutions to train more talented physicians to serve the medical needs of the diverse population in Northeast Ohio.


We want to express our deepest appreciation to UH faculty and staff for your dedication and devotion to training the next generation of healthcare workers. We can also rejoice in the fact that many of our trainees have gone on to become major leaders in science and medicine. To celebrate our trainees, both past and present, UH R&E is pleased to announce the establishment of the UH Alumnus Healthcare Leadership Lecture. The inaugural lecture will be held on Sept. 30, 2021, and will feature UH alum Jonathan Lewin, MD, CEO of Emory Healthcare. I would encourage everyone to join us for this commemorative event.


Sanjay Rajagopalan, MD

Sanjay Rajagopalan, MD is the Division Chief of Cardiovascular Medicine at the UH Harrington Heart and Vascular Institute, Division Chief of Cardiovascular Medicine, and Director of the Center for Advanced Heart and Vascular Care. On May 20, 2021, the American Diabetes Association visited University Hospitals to film Dr. Rajagopalan and the Center for Integrated Novel Approaches in Vascular-Medicine Disease (CINEMA) for the ADA series, “Thought Leadership Film Series.”

In addition to featuring Dr. Rajagopalan in this important series, he was also recognized earlier this year with the American College of Cardiology Distinguished Scientist Award and was elected as a member of the Association of American Physicians, the oldest honorific physician organization in the U.S. As a result, UH R&E interviewed Dr. Rajagopalan to learn more about why he chose to become a cardiologist, the mentors throughout his training, and how he became passionate about patient care and research for the global health issue of diabetes.

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In case you missed the podcast of Life and Leadership: A Conversation with CEO Dr. Cliff Megerian, in our March issue, watch the video below as he shares his medical training journey, career development advice, and key components and collaborations for a successful future at UH.

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Save the date for the inaugural Celebrating Our Training Legacy: The UH Alumni Healthcare Leadership Lecture on Sept. 30, 2021. The inaugural event will feature UH alumni, Jonathan Lewin, MD, CEO of Emory Healthcare.

UH R&E is hosting the 3rd Annual Research & Innovation Day on Nov. 5, 2021. We are pleased to announce Dr. Peter Agre, Nobel Laureate and UH Alumni, will deliver a keynote address at the inaugural UH Distinguished Scientist Lecture.


Daniel Spratt, MD

UH R&E would like to welcome Daniel Spratt, MD, Chairman of the Department of Radiation Oncology, Vincent K. Smith Professor at Case Western Reserve University School of Medicine. Dr. Spratt is a talented physician and scientist who completed his medical training at Vanderbilt University and residency training in Radiation Oncology at Memorial Sloan Kettering Cancer Center. Dr. Spratt is an international expert in prostate cancer and served on the National Comprehensive

Cancer Network (NCCN) prostate cancer guidelines committee, serves as the Chair of the Intact Prostate Cancer Subcommittee within NRG Oncology and the National Cancer Institute’s Genitourinary Steering Committee. He runs an NIH funded translational research team focused on the development and validation of prognostic and predictive biomarkers, has published over 300 peer-reviewed manuscripts, and has served as the principal investigator on numerous national and international clinical trials. He has mentored over 45 students, residents, fellows, and faculty, and has received numerous teaching and mentorship awards.


Clinical Research Center Celebrates Clinical Trial Awareness Week by Painting the System Red

University Hospitals Clinical Research Center (CRC) celebrated its second annual Clinical Trials Awareness Week May 17-21, 2021. The goal of celebrating Clinical Trials Awareness Week was to highlight a specific type of clinical research studies, clinical trials.

CRC Develops Community Advisory Board

Recruiting exclusively through electronic means and word-of-mouth, the UH Clinical Research Center attracted the perfect mix of engaged research allies to develop the UH CRC Community Advisory Board (CAB). CAB will provide candid feedback and commentary on current research practices and 

future projects and initiatives (e.g., the mobile research bus) and provide researchers with the ability to gain access to the opinions and experiences of a diverse group of community members as they develop research protocols, plan recruitment, and establish other facets of their research study or trial that could be viewed as questionable or ethically challenging in processes and/or outcomes.

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David Satcher Clerkship: A National Recruitment Model for Underrepresented Minority Medical Students

In 1991, University Hospital Cleveland Medical Center, a primary affiliate of Case Western Reserve University School of Medicine, created a national recruitment model for underrepresented minority medical students by establishing the David Satcher Clerkship. This recruitment effort aimed to ensure that the diversity of future generations of healthcare leaders receives accurate representation and reflects our institutional pledge to address the needs of underserved and underrepresented communities.

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UH R&E is partnering with UH Ventures to bring you the latest innovation news at UH and in our ecosystem. UH Ventures is the innovation and commercialization arm of University Hospitals. If you have an idea, invention, or just want to learn more about innovation and commercialization, please visit UH Ventures or email UH Ventures Ideas.

Introducing the Health Voyagers Podcast Series: Tech in Ohio

In UH Ventures’ latest episode of its podcast series, UHV President David Sylvan talked to Chris Berry, founder of OhioX to discuss the Cleveland Innovation Project and how the State of Ohio is supporting the advancement of technology across the state.


Stay tuned for more events coming this year focused on Medical Device innovation and Women’s Health, as well as our Innovation on Tap series covering the ins and outs of innovation and commercialization.


Congratulations to the following individuals for their recent grant award and recent achievements:


Jeffrey Dusek, PhD served as a co-editor of a special issue on Effectiveness, Implementation, and Dissemination Research in Integrative Health in the Journal of Alternative and Complementary Medicine.


Marjorie Greenfield, MD was chosen as the inaugural recipient of the Pamela B Davis Senior Achievement and Professional Development Award from the Women Faculty of the School of Medicine at Case Western Reserve University.


Jonathan Lass, MD, Ahmed Omar, MD, Loretta Flynn-Szczotka, OD, PhD, Beth Ann Benetz, MA CRA, Baha Arafah, MD and Vincent Monnier, MD and several other colleagues at UH and CWRU received a 5-year, $6.4M grant from the National Eye Institute which aims to finally determine which diabetic individuals can successfully donate their corneas for keratoplasty (and which should not).


Sanford Markowitz, MD, PhD and Stanton Gerson, MD, co-founders of Rodeo Therapeutics, a drug development start-up company, was recently sold to Amgen Inc. Rodeo develops small-molecule therapies designed to promote repair and regeneration of multiple tissues.


Mahboob Rahman, MD and colleagues received a 5-year $7M NIH-NIDDK grant to form the Cleveland Kidney, Urology and Hematology Training Network, a city-wide collaboration with University Hospitals Cleveland Medical Center, Case Western Reserve University, Cleveland Clinic Foundation, MetroHealth, VA Hospital and Cleveland State University, to give pre and post doc trainees the opportunity to train in a rich, multidisciplinary training program.


Jonathan Shoag, MD was awarded the ASCI Young Physician-Scientist Award from the American Society for Clinical Investigation.


Congratulations to our UH investigators who have authored recent publications. We have total 304 published work from April to June 2021. View the complete list at PubMed.


Graham Bevan, Sanjay Rajagopalan, Sadeer Al-Kindi. Association between ambient air pollution and county-level cardiovascular mortality in the United States by social deprivation index. Am Heart J. May 2021


Natalie Dyer, Jessica Surdam, Jeff Dusek. A Systematic Review of Practiced-Based Research of Complementary and Integrative Health Therapies as Provided for Pain Management in Clinical Settings: Recommendations for the Future and a Call to Action. Pain Medicine. May 2021


Michael Lederman. AIDS in the Heartland-Hemophilia Was the Harbinger of Things to Come. J Acquir Immune Defic Syndr. Apr. 2021


Grace McComsey, Chris Longenecker. Sex, HIV Status, and Measures of Cardiac Stress and Fibrosis in Uganda. J Am Heart Assoc. Jun. 2021


Ehsan Melek, James Driscoll. Novel therapies emerging in oncology to target the TGF-β pathway. J Hematol Oncol. Apr. 2021


Richard Premont, Jonathan Stamler. Red Blood Cell-Mediated S-Nitrosohemoglobin-Dependent Vasodilation: Lessons Learned from a β-Globin Cys93 Knock-In Mouse. Antioxid Redox Signal. Apr. 2021 


Patrick Runnels, Heather Wobbe, Kipum Lee, Randy Jernejcic, Peter Pronovost. Designing for Value in Specialty Referrals: A New Framework for Eliminating Defects and Wicked Problems. N Engl J Medicine Catalyst Jun. 2021


Min-Kyoo Shin, Andrew Pieper. Reducing acetylated tau is neuroprotective in brain injury. Cell. May 2021


David Sweet, Mukesh Jain. Evolutionary Protection of Krüppel-Like Factors 2 and 4 in the Development of the Mature Hemovascular System. Front Cardiovasc Med. May 2021


Have a presentation? Don't forget to use the UH branded PowerPoint templates.


Committed to discovery, team-science and continued educational excellence.


If you have important advancements that should be featured in a future newsletter please e-mail UH R&E.