Offering Clinical Trials for Adults and Children with Asthma
The Division of Pediatric Pulmonology and Allergy/Immunology at University Hospitals Rainbow Babies & Children’s is currently recruiting for a number of asthma-related clinical trials. If you are interested in enrolling in a study or learning more about the opportunities, please complete the form below or contact us directly by phone 216-286-6566 or email Laurie.Logan@uhhospitals.org or Laura.Veri@uhhospitals.org.
Current asthma studies available at UH Rainbow Babies & Children’s include:
SIENA (Steroids In Eosinophil Negative Asthma)
Most people with asthma have inflammation in their airway. Asthma controller medications, like inhaled corticosteroids, are meant to reduce inflammation in the airway. Reducing airway inflammation should make one's breathing easier. However, many people with asthma do not breathe easier when they take an inhaled corticosteroid.
We know that there are several types of cells that can cause airway inflammation. However, inhaled corticosteroids mostly target only one cell called the eosinophil. The purpose of this study is to find out if people should take an asthma controller medication based on the type of inflammatory cells present in their airways.
STICS (Step-up Yellow Zone Inhaled Corticosteroids to Prevent Exacerbations)
Most people with asthma use an action plan to guide their asthma treatment. Written asthma action plans are usually color-coded. “Green” means that asthma symptoms are well controlled. “Yellow” means that asthma symptoms are not well controlled, and asthma treatment may need to change. “Red” means a severe worsening of symptoms. Red zone treatment is usually an oral corticosteroid, like prednisone.
The purpose of this study is to find the best yellow zone action plan strategy for children with asthma, based on the child's asthma symptoms. Finding the best yellow zone strategy may prevent children from entering the red zone and having to take prednisone. The study is also trying to determine which yellow zone strategy leads to the least total corticosteroid (oral and inhaled) use for children with asthma.
The STICS study is currently recruiting children ages 5-11 who have had at least one bad asthma attack in the past year and are receiving low-dose inhaled corticosteroids.
BARD (Best African American Response to Asthma Drugs)
The purpose of this study is to find the best treatment to add for African American/Black people who have asthma that is not well controlled on a low dose of inhaled steroid. The BARD study will also try to find out if African American/Black adults and children differ in how they respond to the medications used in this study. This study is currently recruiting children, teens and adults ages 5 and older who have at least one African American/Black grandparent.
In addition to the clinical trials listed above, the Division of Pediatric Pulmonology and Allergy/Immunology also offers a number of other studies for both adults and children. For additional information on other opportunities, please contact us at 216-286-6566 or email Laurie.firstname.lastname@example.org or Laura.Veri@uhhospitals.org.
If you are interested in learning more about our asthma-related clinical trials, please fill out the form below. A member of our team will be in contact.