Valve & Structural Heart Disease Center

University Hospitals Harrington Heart & Vascular Institute

Alan Markowitz, MD, Cardiac Surgery

Guilherme Attizzani, MD
Angela Davis, RN

Please call Program Coordinator Katherine Burns at 216-844-8448 for appointments and transfers.

Conditions Treated

Aortic stenosis
Mitral regurgitation
Mitral stenosis
Atrial septal defect (ASD)
Patent foramen ovale (PFO) paradoxical stroke


Transcatheter aortic valve replacement (TAVR)
Surgical aortic valve replacement (SAVR)
Valve-in-valve for bioprosthetic valve failure (aortic valve, mitral valve)
Surgical mitral valve replacemen
Mitral/aortic balloon valvuloplasty
ASD closure (catheter and surgical)
PFO closure (catheter)
Left ventricular restoration therapy (LV Parachute)

Distinguishing Features

Multidisciplinary heart team with cardiac surgery and interventional cardiology working side by side
TAVR in “awake and talking” patient: catheterization lab-based procedure with conscious sedation and > 95 percent percutaneous femoral access; average length of stay only two to three days; high-volume center performing more than 200 procedures annually
Leading-edge technologies with partner hospitals in Europe for earliest technology access
Edwards Center of Excellence and Medtronic Center of Excellence for physician TAVR training
National training center for interventional fellows

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