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Mukesh Jain, MD

Mukesh Jain, MD



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  • Chief Academic Officer, University Hospitals
  • Chief Scientific Officer, Harrington Discovery Institute, University Hospitals
  • Professor, CWRU School of Medicine

Mukesh K. Jain, MD is the Chief Academic Officer at University Hospitals Health System and Vice Dean for University Hospital Affairs, Case Western Reserve University. After receiving his medical degree from the University of Buffalo, SUNY Jacobs School of Medicine and Biomedical Sciences, he completed his residency in internal medicine at Beth Israel Deaconess Medical Center. Dr. Jain completed fellowships in research and cardiovascular disease at Harvard School of Public Health and Brigham and Women’s Hospital.

Dr. Jain is widely recognized for pioneering studies establishing KLF proteins as nodal regulators of metabolism, immunity, and aging. He has translated this work from animals to humans and established KLFs as key pharmacologic targets for therapeutic gain. His work has been published in top-tier peer-reviewed journals and he has been continuously supported for 17 years through funding from the National Institutes of Health (including the Outstanding Investigator Award), American Heart Association (including the Established Investigator Award), the Paul G. Allen Frontiers Group, Leducq Foundation, and diverse philanthropic organizations.

Dr. Jain is an elected member of the American Society for Clinical Investigation (ASCI, 2005), American Association of Physicians (AAP, 2009), and National Academy of Medicine (NAM, 2016). He is also recipient of numerous honors including the American Heart Association’s Honorary Russell Ross Memorial Lectureship in Vascular Biology (2012), the North American Vascular Biology Organization’s Judah Folkman Award in Vascular Biology (2015), and the SUNY Buffalo Distinguished Alumnus Award (2016). Dr. Jain is past President of the American Society for Clinical Investigation, one of the oldest honorific physician societies in the country. He is a gifted mentor with mentorship awards from Harvard Medical School and University Hospitals/Case Western Reserve University. Dr. Jain is also the recipient of the Case Western Reserve University's Distinguished University Professor award, the highest honor the university bestows on a member of its professoriate.


  • Cardiovascular Medicine


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Languages Spoken

English, Hindi

Office Locations

Board Certifications

  • Cardiovascular Disease - American Board of Internal Medicine


Fellowship | Cardiovascular Disease
Cardiovascular Disease - Brigham And Women's Hospital (1997 - 1999)

Research Fellowship
Harvard School Of Public Health (1994 - 1997)

Residency | Internal Medicine
Internal Medicine - Beth Israel Deaconess Medical Center (1992 - 1994)

Internship | Internal Medicine
Internal Medicine - Beth Israel Deaconess Medical Center (1991 - 1992)

Medical Education
University At Buffalo Suny Jacobs School Of Medicine And Biomedical Sciences (1991)

State University Of New York At Buffalo (1987)

Industry Relationships

University Hospitals is committed to transparency in our interactions with industry partners, such as pharmaceutical, biotech, or medical device companies. At UH, we disclose practitioner and their family members’ ownership and intellectual property rights that are or in the process of being commercialized. In addition, we disclose payments to employed practitioners of $5,000 or more from companies with which the practitioners interact as part of their professional activities. These practitioner-industry relationships assist in developing new drugs, devices and therapies and in providing medical education aimed at improving quality of care and enhancing clinical outcomes. At the same time, UH understands that these relationships may create a conflict of interest. In providing this information, UH desires to assist patients in talking with their practitioners about industry relationships and how those relationships may impact their medical care.

UH practitioners seek advance approval for certain new industry relationships. In addition, practitioners report their industry relationships and activities, as well as those of their immediate family members, to the UH Office of Outside Interests annually. We review these reports and implement management plans, as appropriate, to address conflicts of interest that may arise in connection with medical research, clinical care and purchasing decisions.

View UH’s policy (PDF) on practitioner-industry relationships.

As of December 31, 2016, Mukesh Jain did not disclose any Outside Relationships with Industry.