We are a national and international leader in research and clinical trials for epilepsy. The findings from our extensive research are translated into the care of our patients, providing rapid access to the latest treatment alternatives.
Current and recent projects include:
- Participating in the pivotal clinical trials of five of the nine antiepileptic drugs brought to market in the past 13 years (lamotrigine, topiramate, felbamate, tiagabine, and levetiracetam)
- Phase 2 and 3 trials of drugs presently under development
- Investigator-initiated studies to compare antiepileptic drugs in terms of efficacy and tolerability
- Use of image guidance to co-register not only MRI but nuclear medicine and EEG data for the safest possible seizure surgery
- Protocols with Case Engineering to study methods of seizure detection
- Researching methods to predict seizures so that treatments could be developed to head off a seizure before it begins; the project is being done in collaboration with Cleveland-based industry and NINDS