Trial
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This research study is designed to learn whether different anti-HIV medication ("HAART") combinations work equally well in participants who have never taken anti-HIV medications before.
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The Addiction Recovery Services of University Hospitals Case Medical Center is conducting clinical research on the treatment of Alcohol Dependence in adults with Bipolar I Disorder, a mood disorder that affects more than
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ALS is a devastating disease that eventually affects respiratory function. Treatment options for respiratory function are limited to no treatment, non-invasive or invasive ventilation. Stimulation of the Diaphragm in Amyotrophic Lateral Sclerosis is an investigation of a diaphragm pacing system
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This research study will examine how atomoxetine (Scrattera) in the treatment of ADHD in adults and how ADHD affects family functioning. Eligible participants who meet screening criteria will be closely monitored with frequent clinical visits with a physician
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This study is designed to determine whether there is an increased incidence of Barrett's esophagus or esophageal cancer in the relatives of persons with Barrett's esophagus or esophageal cancer.
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This research study compares lithium and valproate (Depakote) in the treatment of older adults with bipolar manic (high mood) and hypomanic episodes (slightly high mood)
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This research study will evaluate the usefulness of urodynamic testing which is a test that measures bladder function.
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The purpose of this research study is to learn more about how to care for women who are at increased genetic risk of ovarian cancer.
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This research study is designed to compare two treatments for ovarian, fallopian tube or peritoneal cancers.
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This research study is designed to determine whether combining the drug Tirapazamine with Cisplatin during radiation therapy increases the length of time that patients with cancer of the cervix live without their cancer coming back compared to patients who receive Cisplatin and radiation therapy without receiving Tirapazamine.
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This research study is designed to test the drug Celecoxib in the treatment of cervical intraepithelial neoplasia (CIN 3-a precancerous lesion of the cervix).
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This research study is designed to look at the safety and effectiveness of an oral study drug called AST-120 in participants who have Crohn's disease with a draining fistula
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This research study will examine the use of escitalopram (Lexapro) in the treatment of children suffering from depression.
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This research study is designed to determine whether the study medication will slow the progress of kidney disease in individuals with Type II Diabetes.
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The Skin Study Center of the Department of Dermatology is doing basic research into the cellular causes of hair loss (alopecia).
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FUSION II is a research study for patients who have recently been hospitalized with heart failure. The research study is designed to determine whether a medicine called nesiritide (Natrecor®)
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The goal of this research study is to find out if the drug nicardipine (Cardene®) can be used for the treatment of high blood pressure that occurs after people have suffered a stroke due to sudden bleeding in their brain.
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The HIV Metabolic Research Center is conducting the HIV Lipoatrophy Study to understand how HIV infected adults can avoid the disfigurement of fat loss.
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This research study is designed to learn more about preventing atherosclerosis (hardening of the arteries) in children and young adults with Lupus.
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The Department of Dermatology is conducting an investigational study for patients with lupus that manifests in the skin and affects specific cells in the immune system.
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For nearly 20 years, University Memory and Aging Center researchers have been studying why some people develop problems with memory, thinking, and activities of daily living as they age, while others retain normal memories.
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This research study is designed to determine whether thymectomy (surgical removal of the thymus) helps participants with myasthenia gravis (MG) get better compared to using only medications like prednisone that suppress the immune system.
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This research study is designed for children and adolescents who have experienced a trauma (e.g. sexual/physical abuse, violence, a car accident) and then developed posttraumatic stress disorder (PTSD).
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The Department of Dermatology is conducting research for adults with moderate to severe plaque psoriasis to evaluate the safety and effectiveness of a medication that is a subcutaneous injection (just underneath the skin).
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The Department of Dermatology is conducting a research study to evaluate the effects of a cream applied to the skin for the treatment of psoriasis.
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The Department of Dermatology is conducting research for adults with moderate to severe plaque psoriasis to evaluate the safety and effectiveness of a medication that is a subcutaneous injection (just underneath the skin).
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The Skin Study Center in the Department of Dermatology is conducting a research study for adults with Actinic keratoses (AK), Bowen's disease, Squamous cell carcinoma, Basal cell carcinoma, or Mycosis fungoides (MF stages IA, IIA, IB, or IIB).
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The Skin Study Center of the Department of Dermatology is doing basic research into the cellular causes of psoriasis.
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"Electrical activation of the diaphragm for ventilatory assist" is a clinical research study investigating a new diaphragm pacing system in quadriplegic patients who require a mechanism ventilator.
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The Neurological Institute Clinical Trials Unit is conducting a research study to find out if treatment with either aspirin alone or aspirin and Plavix® help to prevent another stroke in people who recently suffered a "lacunar stroke&qu
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This research study is designed to compare two treatments for inidividuals who have a Patent Foramen Ovale (PFO; an opening in the heart) and who had a recent stroke.
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Standard rehabilitation does not restore normal, safe walking to many stroke survivors. Functional Neuromuscular Stimulation (FNS), using intramuscular electrodes (applying electrical stimulation to the muscles), has been shown to help retrain walking patterns for people who have had a stroke more than one year ago.
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This research study is designed to improve arm function after stroke. Two types of treatment will be offered: 1) robotics motor learning (ROB ML); and 2) FNS motor learning (FNS ML).
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The Department of Neurology is conducting a research study to determine whether pioglitazone, a medication used to treat diabetes, may help prevent another stroke in patients who have been diagnosed with insulin resistance and who have already
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The Longitudinal Study of Urea Cycle Disorders (UCDs) will follow individuals with UCDs so that more can be learned about the natural history of all eight forms of the disorder.
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This research study will use blood tests and (optional) ultrasound imaging to help doctors learn more about hormone levels and other aspects of ovarian structure and function before, during, and after chemotherapy.
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This research study will evaluate a topical knee patch compared with placebo in treating patients who have OA of the knee.
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This research study will evaluate the safety and efficacy of an injectable drug in the treatment of subjects with rheumatoid arthritis who have an inadequate response to TNF- therapy.
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This research study will evaluate the performance of a Walking Model of Osteoarthritis (OA) while walking on a treadmill.
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Infected or contaminated hernias
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A Randomized trial of Vitamin D and Calcium therapy versus Placebo and Calcium in patients 60 years or older with Heart Failure from any cause.
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AREDS 2 - Age-Related Eye Disease Study 2: An investigative study of the effects of oral supplements of lutein/zeaxanthin and omega-3 fatty acids for the treatment of dry AMD.
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The purpose of this research is to determine if ranibizumab alone or with laser photocoagulation is more efficacious than photocoagulation alone for the treatment of Diabetic Macular Edema.
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The purpose of this research is to determine if Intravitreal triamcinolone acetonide or intravitreal ranibizumab will reduce the magnitude of visual acuity loss in patients with Diabetic Macular Edema.
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The Mood Disorders Program of University Hospitals Case Medical Center is conducting clinical research on the treatment of symptoms related to Generalized Anxiety Disorder and Bipolar Disorder with or without Substance Use Disorder.
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The Mood Disorders Program of University Hospitals Case Medical Center is conducting clinical research on the treatment of symptoms related to Major Depressive Disorder with Generalized Anxiety.
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The Mood Disorders Program of University Hospitals Case Medical Center is conducting an observational study related to Treatment Resistant Depression (TRD), which is defined as being in the current episode of depression for the past 2 years or longer, and having failed trials of at least 4 medications for depression.
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The Mood Disorders Program of University Hospitals Case Medical Center is building a Registry to collect demographic information on a wide cross section of patients with a mood disorder.
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The Mood Disorders Program of University Hospitals Case Medical Center is conducting clinical research on the treatment of symptoms related to Bipolar Disorder, a mood disorder that affects more than four million people in the United States.
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The Mood Disorders Research Program of University Hospitals Case Medical Center is conducting clinical research on the treatment of symptoms related to Major Depressive Disorder.
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The Mood Disorders Program of University Hospitals Case Medical Center is building a Registry to collect demographic information on a wide cross section of patients with a mood disorder.
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The study is a randomized, parallel group, unblinded, multicenter study that compares two approaches [home-based, portable monitoring (PM) versus attended, laboratory-based polysomnography (PSG) (Lab)] in adults, at least 18 years of age, with a moderate to high probability of obstructive sleep apnea (OSA) and who have been referred to sleep medicine specialists at AASM-accredited sleep centers for evaluation and/or management.
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Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist
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A Multi-Center, Single-Blind, Randomized Study Comparing Thymectomy to No Thymectomy in Non-Thymomatous Myasthenia Gravis (MG) Patients Receiving Prednisone
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ARIES-3: A Phase 3, Long-term, Open-label, Multicenter Safety and Efficacy Study of Ambrisentan in Subjects with Pulmonary Hypertension
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REVEAL Registry (Registry to EValuate Early and Long-Term PAH Disease)
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The purpose of this research study is to understand how immune responses within the lung protect against respiratory infection with Mycobacterium tuberculosis, the organism that causes tuberculosis (Tb).
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The purpose of this research study is to clarify the cause of the multi-organ inflammatory disease sarcoidosis.
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